Results 101 to 110 of about 962,402 (283)

ISSUES IN ACHIEVING TARGETED FUNDING FOR LEADING SCIENTISTS AND SCIENTIFIC COMMUNITIES USING INDEXES OF PUBLICATION ACTIVITY

open access: yesEkonomika Nauki, 2016
In order to increase the competitiveness of the Russian scientific-technological complex in the global environment, it is planned to increase competition through State funding, spent on research and development.
N. G. Kurakova, O. G. Grigor’ev
doaj  

DESEMPREGO E QUALIFICAÇÃO DA MÃO DE OBRA NO BRASIL

open access: yesRevista de Economia Contemporânea
RESUMO Baseado no cenário do mercado de trabalho brasileiro na última década e inspirado pelas teorias da Busca do Emprego e do Capital Humano, o artigo em questão objetiva analisar o desemprego no Brasil através da perspectiva da qualificação da mão de ...
João Paulo Faria de Araújo   +1 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Qualification of improved joint heaters [PDF]

open access: yes
Qualification testing of the Redesigned Solid Rocket Motor improved igniter-to-case joint and field joint heaters was conducted on the fired TEM-04 static test motor and was completed on 7 Sep. 1989.
Cook, M.
core   +1 more source

The Transformation of Work—Conducting and Aggregating Research on Human Resources in SMEs Facing Transformation Pressure

open access: yesMerits
Rarely do so many areas of society change as quickly as now. This study analyses the disruptive transformation of HR/qualification in small and medium-sized enterprises (SMEs) in the leading sectors of mechanical and plant engineering and the automotive ...
Fabienne Riesel   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Pulse of Equality: A Snapshot of U.S. Perspectives on Gay and Transgender People and Policies [PDF]

open access: yes, 2008
Presents survey findings on attitudes toward and beliefs about gays and lesbians, as well as policies including legal recognition of gay couples, adoption qualification, and anti-discrimination laws, by gender, age, race/ethnicity, and ...

core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

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