Results 191 to 200 of about 891,174 (285)

Northern Ireland qualifications quarterly : October – December 2012 [PDF]

, 2013
Fisher, Alison
core  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

The educational attainment of autistic individuals and individuals with high autistic traits: A study of 230,000 people in the United Kingdom

Weir E, White S, Matthews F, Procyshyn T, Allison C, Baron-Cohen S.   +5 more
europepmc   +1 more source

Challenges in implementing new nursing qualifications (Regulation 174) in South African public nursing colleges: Principal perspectives. [PDF]

Curationis
Poto-Rapudi MN, Masango TE, Mbombi MO.
europepmc   +1 more source

Pilot qualifications: guidance for awarding bodies [PDF]

, 2008

core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Navigating Professional Aspirations: The Role of Work-Family Conflict, Job Demand and Control, and Social Support in Shaping Nursing Students' Career Intentions. [PDF]

J Nurs Manag
Gilchrist A, Večerková D, Pokorná A, Riad A.   +3 more
europepmc   +1 more source

Implementing the Qualifications and Credit Framework [PDF]

, 2007

core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Prerequisites for primary care in obesity counselling and management: a quantitative, exploratory survey of general practitioners in the federal Republic of Germany. [PDF]

BMC Prim Care
Wangler J, Jansky M.
europepmc   +1 more source