Results 51 to 60 of about 7,113,012 (334)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

The Gender Dimension of Women’s Lingual Behaviorin Polylingual Families and Partnerships

Політичні дослідження, 2021
The typical studies on national and language issues have a focus on macro-level of social structure. Despite the large number of available studies on gender inequality, in Ukraine in particular, the issue of including the gender aspect in the contextof ...
Anastasiia Molotsiian, Volodymyr Shelukhin   +1 more
doaj   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Sharing Qualitative and Qualitative Longitudinal Data in the UK: Archiving Strategies and Development [PDF]

, 2011
Over the past two decades significant developments have occurred in the archiving of qualitative data in the UK. The first national archive for qualitative resources, Qualidata, was established in 1994.
Bishop, Libby, Neale, Bren
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Psychological meanings reported by patients with Graves’ Disease in hyperthyroidism but without ophthalmopathy about their quotidian life: A qualitative study conducted in a Brazilian university specialized outpatient service

European Psychiatry
Introduction To handle well clinical treatments, it is crucial to know the expectations of patients who seek help. We need to ask ourselves: how do patients interpret subjectively their diagnosis, treatments, and self-care?
L. S. Valladão, F. S. Silva, C. F. Casagrande, L. M. Guerra, D. E. Zantut-Wittmann, E. R. Turato   +5 more
doaj   +1 more source

Measuring dispersion in the context of ordered qualitative scales [PDF]

, 2018
Producción CientíficaThe main purpose of this contribution is to measure the dispersion associated with the different results of a variable when they form a set of linguistic terms obtained after examining different qualities of people, services, etc ...
Borge González, Luis Moisés, García Lapresta, José Luis   +1 more
core   +1 more source

Fuzzy qualitative simulation with multivariate constraints [PDF]

, 2014
Postprin
Coghill, George M, Pang, Wei
core   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Qualitative Theory for Lensed QSOs

, 2003
We show that some characteristics of multiply-imaged QSO systems are very model-independent and can be deduced accurately by simply scrutinizing the relative positions of images and galaxy-lens center.
Claeskens J.-F., Liliya L. R. Williams, Prasenjit Saha, Saha P., Schneider P.   +4 more
core   +1 more source