Results 71 to 80 of about 9,020,184 (250)

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Bridging Conceptions of Quality in Moments of Qualitative Research

, 2013
Quality assessment in qualitative research has been, and remains, a contentious issue. The qualitative literature contains a diversity of opinions on definitions of and criteria for quality.
Ravenek, Michael John, Laliberte Rudman, Debbie   +1 more
core   +1 more source

Geosite Assessments at the Southern Part of Karangbolong Dome: New Insight to Geotourism Potential in Kebumen, Central Java, Indonesia

JGEET: Journal of Geoscience, Engineering, Environment and Technology, 2020
Karangbolong is a morphological dome in Kebumen area, that has a high geological diversity and have a lot of tourism potential, but has not been developed optimally as a geotourism potential based on conservative and educative aspects, especially the ...
Fadlin, Gentur Waluyo, Yohanes Iwan, Nita Ariyanti, Nanda Ajeng Nurwantari   +4 more
doaj   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Arctic Monitoring and Assessment Programme Assessment 2013: Arctic Ocean Acidification

, 2013
Report documenting the findings and recommendations of the first comprehensive assessment of Arctic Ocean acidification (AOA) conducted by the Arctic Monitoring and Assessment Programme (AMAP).
Arctic Monitoring and Assessment Programme
core  

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Qualitative assessment for extrapersonal neglect in patients with stroke using a virtual reality system task

Cogent Medicine, 2019
We investigated whether our virtual reality (VR) system task could detect extrapersonal neglect in patients with stroke and attempted to determine which targets were easiest/most difficult to detect for patients with unilateral spatial neglect.
Masaki Tamura, Makoto Shirakawa, Zhi-wei Luo, Kazue Noda, Rumi Tanemura   +4 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Setting a protocol for hazelnut roasting using sensory and colorimetric analysis: Influence of the roasting temperature on the hazelnut quality Tonda Gentile delle Langhe cv.

Czech Journal of Food Sciences, 2013
The influence of roasting temperature on the final quality of Piedmont hazelnut (cultivar Tonda Gentile delle Langhe) was evaluated. Sensory and colorimetric analyses were performed to define a quality profile of the fruit relating to the roasting ...
Dario DONNO, Gabriele L. BECCARO, Gabriella M. MELLANO, Sara Di PRIMA, Massimiliano CAVICCHIOLI, Alessandro K. CERUTTI, Giancarlo BOUNOUS   +6 more
doaj   +1 more source