Results 101 to 110 of about 26,843,223 (307)

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Tackling neighborhood health inequalities in the UK through cross-sector collaborations and community engagement: thematic synthesis of focus group and questionnaire data

Frontiers in Public Health
BackgroundCommunity engagement has become an increasingly common approach to addressing health inequalities. A three-phase UK-wide interdisciplinary, multicentered program of research, “Mobilizing Community Assets to Tackle Health Inequalities,” was ...
Linda J. M. Thomson, Linda J. M. Thomson, Rabya Mughal, Helen J. Chatterjee, Helen J. Chatterjee   +4 more
doaj   +1 more source

Ethnographic Reflections of Return Migration in a Romanian Rural Community

Dve Domovini, 2017
The objective of the research is to describe the return migration process in a Romanian rural community; we will focus here on the identity changes experienced by community members who recently returned from Italy.
Florentina Scarneci Domnisoru, Codrina Csesznek   +1 more
doaj   +1 more source

Conflicts in qualitative research

, 2014
Volume 12 of the Qualitative Psychology Nexus series presents contributions to the XIV. Workshop on Qualitative Research in Psychology on the general topic of "Conflicts in Qualitative Research." It was organized by the Center for Qualitative Psychology ...
Huber, Günter L., Pérez Navío, Eufrasio, López Gómez, Ernesto, Domínguez Garrido, María Concepción, Sládková, Jana, Medina Rivilla, Antonio, Medina Domínguez, Conchita, Jiménez-Garrido, Amador, Colmenero Ruiz, María Jesús, Khan, Shahjehan, Medina Domínguez, María, Pegalajar Palomino, María del Carmen, Santoro Moreno, José María   +12 more
core   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Potentials and Limits of Secondary Analysis in a Specific Applied Context: The Case of EDF—Verbatim

Forum: Qualitative Social Research, 2005
In this paper we present the results of secondary analyses conducted on documents recorded in VERBATIM, the qualitative data archiving system and database developed by the Sociological Surveys Department (GRETS) of Electricité de France (EDF).
Magdalini Dargentas, Dominique Le Roux
doaj  

Qualitative Psycholgy Nexus Vol. VIII: Epistemologies for Qualitative Research

, 2011
The 9th annual meeting of the Center for Qualitative Psychology was held in Northern Finland, near to the city of Oulu. The seminar was started with two crucial questions leading the participants to the theme of the conference.
Suorsa, Teemu, Huber, Günter L., Maxwell, Joseph, Medina, Antonio, Schweizer, Karin, Feliz, Tiberio, Pavlovic, Jelena, Kronqvist, Eeva-Liisa, Feliz, Sálvora, Pina, Jorge, Gento, Samuel, Domínguez, María Concepción, Soini, Hannu, Ricoy, María Carmen, Korte, Petra, Kiegelmann, Mechthild   +15 more
core   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source