Results 61 to 70 of about 26,843,223 (307)

A question of respect: A qualitative text analysis of Canadian parliamentary committee hearings on PCEPA

open access: yes, 2017
Project Summary: The overarching research question that we address in our paper, “A Question of Respect: A Qualitative Text Analysis of the Canadian Parliamentary Committee Hearings on The Protection of Communities and Exploited Persons Act (PCEPA ...
Fuji Johnson, Genevieve
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Qualitative data for examining fixed and incremental concepts of language learning: A search for the stories behind students’ motivation

open access: yesIndonesian Journal of Applied Linguistics, 2018
Although quantitative tools are often employed to examine students’ beliefs in language learning, qualitative interviews can offer further depth and insight on these beliefs, by shedding light on the detail of the experiences behind student perceptions ...
Laura V. Fielden Burns   +1 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Improving Student Learning Through Professional Learning Communities: Employing a System-Wide Approach

open access: yesCanadian Journal for New Scholars in Education, 2019
Effective Professional Learning Communities (PLCs) contribute to the overall improvement of student learning when a system-wide, leadership-based approach from the district and school level is applied by aligning a common vision, goal, and purpose ...
Gregory David Paterson
doaj  

Analysing and presenting qualitative data [PDF]

open access: yesBritish Dental Journal, 2008
This paper provides a pragmatic approach to analysing qualitative data, using actual data from a qualitative dental public health study for demonstration purposes. The paper also critically explores how computers can be used to facilitate this process, the debate about the verification (validation) of qualitative analyses and how to write up and ...
Burnard, P   +4 more
openaire   +3 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Development and content validity of the Experienced Patient‐Centeredness Questionnaire (EPAT)—A best practice example for generating patient‐reported measures from qualitative data

open access: yesHealth Expectations, 2022
Introduction To effectively foster patient‐centeredness (PC), it is crucial to measure its implementation. So far, there is no German measure to assess PC comprehensively.
Eva Christalle   +6 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Integrating Sustainability Pillars Into Trial Design Decision‐Making: Results of an International Survey

open access: yesClinical and Translational Science
The pharmaceutical industry is increasingly shifting to decentralized clinical trials (DCTs) conducted at the patient's home, sometimes including trial material home delivery.
Pritibha Singh   +3 more
doaj   +1 more source

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