Results 91 to 100 of about 238,910 (267)

Query-Based Analysis: A Strategy for Analyzing Qualitative Data Using ChatGPT

open access: yesQualitative Health Research
ChatGPT is a recently introduced artificial intelligence program that is gaining broad popularity across a number of fields, one of which is the analysis of qualitative data in health-related research. Traditionally, many forms of qualitative data have relied on a detailed process of coding the data by labeling small segments of the data, and then ...
openaire   +2 more sources

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin   +11 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro   +14 more
wiley   +1 more source

SURVEI MANAJEMEN SARANA DAN PRASARANA DI STADION JATIDIRI KOTA SEMARANG PADA TAHUN 2013

open access: yesActive: journal of physical education, sport, health and recreation, 2015
This study used qualitative methods , as it aims to describe the role of management : planning ( planning) , organizing ( organizing ) , directing ( leading) and monitoring ( controlling) through rationalization of the number of existing facilities and ...
Baharudin Yusuf Putra Setyawan
doaj  

Challenges of e-sports based on big data and qualitative analyses:

open access: yesSouth African Journal for Research in Sport, Physical Education and Recreation
e-Sports has become one of the fastest-growing segments of the sports industry. However, the research trends in e-sports rely heavily on traditional research trends in sport management. Therefore, the purpose of this study was to generate a strategic development plan for e-sports based on an in-depth analysis of the current status of the e-sports ...
Seong-Hee Park, Daniel F. Mahony
openaire   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright   +10 more
wiley   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova   +9 more
wiley   +1 more source

The role of pedagogical knowledge base, creativity, and resilience in shaping EFL teachers’ self-efficacy

open access: yesFrontiers in Education
Teacher self-efficacy is essential for effective English as a Foreign Language (EFL) teaching, particularly in Kazakhstan's multilingual educational environment. This study examined the relationships between pedagogical knowledge base, teacher resilience,
Kuralay Kenzhekanova   +4 more
doaj   +1 more source

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