Results 51 to 60 of about 5,937,506 (332)

New directions in qualitative research ethics [PDF]

, 2017
No abstract ...
Kara, Helen, Pickering, Lucy
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Comprehensive sexuality education for the most disadvantaged young people: findings from formative research in Ethiopia

Sexual and Reproductive Health Matters, 2023
Comprehensive sexuality education (CSE) seeks to improve young people’s knowledge, attitudes and practices in relation to sexual and reproductive health, sexual and social relationships, and dignity and rights. In Ethiopia, young people with disabilities
Kate Pincock, Workneh Yadete, Darwit Girma, Nicola Jones   +3 more
doaj   +1 more source

Methods for the thematic synthesis of qualitative research in systematic reviews [PDF]

, 2007
Background There is a growing recognition of the value of synthesising qualitative research in the evidence base in order to facilitate effective and appropriate health care.
A Bryman, A Cobb, A Daly, A Harden, A Harden, A Harden, A Harden, A Harden, A Oakley, A Oakley, Angela Harden, B Paterson, C Marston, C Mulrow, C Seale, EPPI-Centre, GW Noblit, H Cooper, H White, I Chalmers, I Chalmers, J Barroso, J Popay, J Popay, J Shepherd, J Thomas, J Thomas, J Thomas, J Thomas, James Thomas, K Strike, L Spencer, LA Walters, LH Doyle, M Boulton, M Dixon-Woods, M Dixon-Woods, M Dixon-Woods, M Egger, M Fisher, M Hammersley, M Newman, M Petticrew, M Sandelowski, M Sandelowski, M Sandelowski, Medical Sociology Group, N Britten, N Mays, P Alderson, P Davies, P Juni, R Campbell, R Dixey, R Rees, RE Boyatzis, S Thorne, SSL Wong, V Braun   +58 more
core   +9 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The qualitative orientation in medical education research [PDF]

, 2017
Peer reviewedPublisher ...
Cleland, Jennifer Anne
core   +3 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Emotional meanings attributed to sexual experiences reported by Brazilian Men with Head and Neck Cancer seen at a Public University Oncologic Outpatient Service: A Qualitative Study

European Psychiatry
Introduction “What can and what cannot I do in a sexual relationship?” |In this way, a middle-aged man with HNC - Head and Neck Cancer, under chemotherapy or radiotherapy, asks.
R. S. E. Sant’Ana, C. S. P. Lima, E. R. Turato   +2 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Qualitative Environmental Health Research: An Analysis of the Literature, 1991-2008 [PDF]

, 2010
BACKGROUND. Recent articles have advocated for the use of qualitative methods in environmental health research. Qualitative research uses nonnumeric data to understand people's opinions, motives, understanding, and beliefs about events or phenomena ...
Arcury TA, Evans D, Haines MM, Halvorson SJ, Higgins JPT, Larsson LS, Lobdell DT, MacQueen KM, Madeleine Kangsen Scammell, Patton MQ, Peterson CL, Petitti DB, Phaswana-Mafuya N, Snape D, Stemler S, Tu K, Ulin PR, Wing S   +17 more
core   +5 more sources