Results 51 to 60 of about 5,385,043 (357)

Matrix: a complex amalgam of structures and functions in tumor microenvironment

open access: yesFEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis   +3 more
wiley   +1 more source

Comprehensive sexuality education for the most disadvantaged young people: findings from formative research in Ethiopia

open access: yesSexual and Reproductive Health Matters, 2023
Comprehensive sexuality education (CSE) seeks to improve young people’s knowledge, attitudes and practices in relation to sexual and reproductive health, sexual and social relationships, and dignity and rights. In Ethiopia, young people with disabilities
Kate Pincock   +3 more
doaj   +1 more source

Finding qualitative research: an evaluation of search strategies [PDF]

open access: yes, 2004
BACKGROUND: Qualitative research makes an important contribution to our understanding of health and healthcare. However, qualitative evidence can be difficult to search for and identify, and the effectiveness of different types of search strategies is ...
Alex J Sutton   +10 more
core   +6 more sources

Qualitative doctoral research in educational settings: reflecting on meaningful encounters [PDF]

open access: yes, 2020
In qualitative doctoral research the methodological approach, and the research design are extremely important when ensuring the rigorousness of the work.
Kambouri-Danos, Maria, Pieridou, Myria
core   +4 more sources

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

open access: yesFEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu   +9 more
wiley   +1 more source

Qualitative Research in CALL [PDF]

open access: yesCALICO Journal, 2015
This introduction to the Special Issue of the CALICO Journal positions research in Computer Assisted Language Learning (CALL) in the wider field of qualitative and quantitative approaches to research. It discusses the merits of the different approaches and links them to research paradigms that dominate the different subject areas constituting CALL ...
Stickler, Ursula, Hampel, Regine
openaire   +3 more sources

Trends in qualitative research in language teaching since 2000 [PDF]

open access: yes, 2009
This paper reviews developments in qualitative research in language teaching since the year 2000, focusing on its contributions to the field and identifying issues that emerge.
Aline   +111 more
core   +1 more source

Semi‐automated hippocampal avoidance whole‐brain radiotherapy planning

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background Hippocampal avoidance whole‐brain radiotherapy (HA‐WBRT) is designed to spare cognitive function by reducing radiation dose to the hippocampus during the treatment of brain metastases. Current manual planning methods can be time‐consuming and may vary in quality, necessitating the development of automated approaches to streamline ...
Dong Joo Rhee   +9 more
wiley   +1 more source

UR‐cycleGAN: Denoising full‐body low‐dose PET images using cycle‐consistent Generative Adversarial Networks

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose This study aims to develop a CycleGAN based denoising model to enhance the quality of low‐dose PET (LDPET) images, making them as close as possible to standard‐dose PET (SDPET) images. Methods Using a Philips Vereos PET/CT system, whole‐body PET images of fluorine‐18 fluorodeoxyglucose (18F‐FDG) were acquired from 37 patients to ...
Yang Liu, ZhiWu Sun, HaoJia Liu
wiley   +1 more source

Psychological meanings reported by patients with Graves’ Disease in hyperthyroidism but without ophthalmopathy about their quotidian life: A qualitative study conducted in a Brazilian university specialized outpatient service

open access: yesEuropean Psychiatry
Introduction To handle well clinical treatments, it is crucial to know the expectations of patients who seek help. We need to ask ourselves: how do patients interpret subjectively their diagnosis, treatments, and self-care?
L. S. Valladão   +5 more
doaj   +1 more source

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