Results 41 to 50 of about 2,905,709 (315)

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

The Use of Qualitative Content Analysis in Case Study Research

, 2006
This paper aims at exploring and discussing the possibilities of applying qualitative content analysis as a (text) interpretation method in case study research.
Florian Kohlbacher, Kohlbacher, Florian
core   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Response to written feedback of clinical data within a longitudinal study: a qualitative study exploring the ethical implications [PDF]

, 2011
Background There is a growing ethical imperative to feedback research results to participants but there remains a striking lack of empirical research on how people respond to individualised feedback. We sought to explore longitudinal study participants’
Anderson, Annie, Benzeval, Michaela, Michaela Benzeval, Gray, Cindy M., Lorimer Karen, Karen Lorimer, Anderson Annie, Hunt, K., Sally Wyke, Gray Cindy M, Wyke, S., Hunt Kate, Annie Anderson, Wyke Sally, Anderson, A.S., Lorimer, Karen, Cindy M Gray, Anderson, Annie; id_orcid, Gray, C.M., Hunt, Kate, Anderson, Annie S., Benzeval, M., Gray, Cindy M, Wyke, Sally, Benzeval Michaela, Lorimer, K., Kate Hunt   +26 more
core   +1 more source

The Level of Computer Use and the Degree of the Acceptance of Informatics Applied in Medical Research [PDF]

Applied Medical Informatics, 2008
Young medical graduates are bound to become researchers, as medical science implies constant studying. Documenting, collecting and processing medical data involve a certain degree of computer literacy. The development of computer-assisted tools and their
Vladimir BACÂREA, Tudor CĂLINICI, Cosmin MOLDOVAN, Horea SABĂU, Marius MĂRUŞTERI   +4 more
doaj  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Application of Haddon’s matrix in qualitative research methodology: an experience in burns epidemiology [PDF]

Background: Little has been done to investigate the application of injury specific qualitative research methods in the field of burn injuries. The aim of this study was to use an analytical tool (Haddon’s matrix) through qualitative research methods to ...
عرشی, شهنام, صادقی, همایون, محمدی, رضا, دلجوان, رضا, فولادی, نسرین   +4 more
core   +1 more source

Inflammatory Bowel Diseases (IBDs) vs Irritable Bowel Syndrome (IBS): A comparative qualitative study on prevalent themes, emotions and Quality of Life (QoL) [PDF]

Journal of Health and Social Sciences
Introduction: Inflammatory bowel diseases (IBDs) (including Crohn’s disease, Ulcerative colitis) and Irritable Bowel Syndrome (IBS) are different debilitating conditions affecting the digestive system.
Amelia RIZZO, Aurora MAUTONE, Francesco CHIRICO, Lukasz SZARPAK, Michal PRUC, Maria Grazia MAGGIO, Livio TARCHI, Kavita BATRA, Giuseppe FERRARI, Francesca BRUNO, Aldo SITIBONDO   +10 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source