Results 31 to 40 of about 1,413,485 (300)

A Pilot Cost-Effectiveness Analysis of Treatments in Newly Diagnosed High-Grade Gliomas: The Example of 5-Aminolevulinic Acid Compared With White-Light Surgery [PDF]

, 2015
BACKGROUND: High-grade gliomas are aggressive, incurable tumors characterized by extensive diffuse invasion of the normal brain parenchyma. Novel therapies at best prolong survival; their costs are formidable and benefit is marginal.
Alves, M, Castel-Branco, M, Esteves, S, Stummer, W   +3 more
core   +1 more source

Effective diabetes complication management is a step toward a carbon-efficient planet: an economic modeling study [PDF]

, 2020
Background The management of diabetes-related complications accounts for a large share of total carbon dioxide equivalent (CO2e) emissions. We assessed whether improving diabetes control in people with type 2 diabetes reduces CO2e emissions, compared ...
Chatterjee, Mou, Dhatariya, Ketan, Fordham, Ric, Gains, Mike, Haagen Panton, Ulrik, Lloyd, Adam, Mathew, Mevin, Stancliffe, Rachel, Taneja, Loveleen   +8 more
core   +1 more source

Cost-effectiveness of a patient-centred approach to managing multimorbidity in primary care:a pragmatic cluster randomised controlled trial [PDF]

, 2020
Objective Patients with multiple chronic health conditions are often managed in a disjointed fashion in primary care, with annual review clinic appointments offered separately for each condition.
Bower, Peter, Brookes, Sara, Chaplin, Katherine, Fitzpatrick, Bridie, Gardner, Caroline, Gaunt, Daisy, Guthrie, Bruce, Hollinghurst, Sandra, Lee, Victoria, Man, Mei-See, Mercer, Stewart W., Salisbury, Chris, Thorn, Joanna   +12 more
core   +6 more sources

Sociodemographic differences in symptom severity and duration among women referred to secondary care for menorrhagia in England and Wales: a cohort study from the National Heavy Menstrual Bleeding Audit. [PDF]

, 2018
OBJECTIVE: To examine symptom severity and duration at time of referral to secondary care for heavy menstrual bleeding (HMB) by socioeconomic deprivation, age and ethnicity DESIGN: Cohort analysis of data from the National HMB Audit linked to Hospital ...
Bansi-Matharu, Loveleen, Cromwell, David A, Geary, Rebecca Sally, Gurol-Urganci, Ipek, Kiran, Amit, Mahmood, Tahir, Shakespeare, Judy, van der Meulen, Jan   +7 more
core   +2 more sources

An exploratory study to estimate cost-effectiveness threshold value for life saving treatments in western Iran

Cost Effectiveness and Resource Allocation, 2020
Background Cost-effectiveness analysis provides a crucial means for evidence-informed decision-making on resource allocation. This study aims to elicit individuals' willingness to pay (WTP) for one additional quality-adjusted life-year (QALY) gained from
Najmeh Moradi, Abraha Woldemichael, Parisa Malekian, Delnia Moradi Rotvandi, Satar Rezaei   +4 more
doaj   +1 more source

Quality-Adjusted Life-Years without Constant Proportionality [PDF]

Value in Health, 2018
A quality-adjusted life-year is a common unit of measurement in health valuation. Under its constant proportionality assumption, the value of a quality-adjusted life span is defined as the product of preference weight and life span.To empirically identify an alternative functional relationship between life span and value by relaxing the constant ...
Craig, Benjamin M., Rand, Kim, Bailey, Henry, Stalmeier, P.F.M.   +3 more
openaire   +3 more sources

Impact of Potentially Inappropriate Prescribing on Adverse Drug Events, Health Related Quality of Life and Emergency Hospital Attendance in Older People Attending General Practice: A Prospective Cohort Study. [PDF]

, 2016
BACKGROUND: Potentially inappropriate prescribing (PIP) describes medications where risk generally outweighs benefit for older people. Cross-sectional studies suggest an association between PIP and poorer health outcomes but there is a paucity of ...
Bennett, Kathleen, Fahey, Tom, McDowell, Ronald, Smith, Susan M, Wallace, Emma   +4 more
core   +4 more sources

THE USE OF QALY AS AN INTEGRAL MEASURE OF EFFECTIVENESS IN THE EVALUATION OF MEDICAL TECHNOLOGIES

Фармакоэкономика, 2017
This report addresses the ways of calculating QALY (Quality-adjusted life-year). OutsideRussia, a standardized methodology to calculate QALY is in use; such an approach makes it possible to apply this universal criterion of effectiveness to the ...
N. Z. Musina, V. K. Fedyaeva
doaj   +1 more source

Where’s WALY? : A proof of concept study of the ‘wellbeing adjusted life year’ using secondary analysis of cross-sectional survey data [PDF]

, 2016
Background The Quality-Adjusted Life Year (QALY) is a measure that combines life extension and health improvement in a single score, reflecting preferences around different types of health gain.
A Appels, A Clarke, A Zajacova, Aileen Clarke, Chris Stinton, D Papaioannou, D Watson, David Jenkinson, DM Crone, EL Idler, EuroQoL Group, F Taggart, FA Huppert, G Lindsay, GR Barton, H Maheswaran, HJ Braiden, HM Agt van, J Brazier, J Brazier, J Collins, J Powell, J Schnittker, J Tosh, JA Johnson, Jason Madan, JHP Hoffmeyer-Zlotnik, JM Haro, KB DeSalvo, L Longworth, L Longworth, M Bharmal, M Herdman, MF Janseen, MJ Crawford, MS Kaplan, N Odou, NP Hurst, P Dolan, P Kind, P Kind, R Brooks, R Core Team, R Rabin, R Tennant, Rebecca Johnson, Sarah Stewart-Brown, SI Saarni, Sian Taylor-Phillips, X Robin, Y Chida   +50 more
core   +3 more sources

Comparative cost-effectiveness of cabozantinib as second-line therapy for patients with advanced hepatocellular carcinoma in Germany and the United States

BMC Gastroenterology, 2020
Background Cabozantinib was approved by the European Medicines Agency and the Federal Drug Administration as an option for sorafenib-resistant advanced hepatocellular carcinoma, increasing overall survival and progression-free survival compared with ...
Maximilian Sieg, Michael Hartmann, Utz Settmacher, Habibollah Arefian   +3 more
doaj   +1 more source