The aim was to develop a methodology for determining the willingness to pay threshold (WTPT) and its upper limit value within the Russian health care system.Materials and methods. WTPT was calculated based on the shadow budget price (i. e.
T. S. Teptsova+5 more
doaj +1 more source
A Pilot Cost-Effectiveness Analysis of Treatments in Newly Diagnosed High-Grade Gliomas: The Example of 5-Aminolevulinic Acid Compared With White-Light Surgery [PDF]
BACKGROUND: High-grade gliomas are aggressive, incurable tumors characterized by extensive diffuse invasion of the normal brain parenchyma. Novel therapies at best prolong survival; their costs are formidable and benefit is marginal.
Alves, M+3 more
core +1 more source
Background The burden of chronic diseases is rapidly rising, both in terms of morbidity and mortality. This burden is disproportionally carried by socially disadvantaged population subgroups.
Lisa Van Wilder+6 more
doaj +1 more source
Background: Respiratory syncytial virus (RSV) is one of the leading causes of pediatric hospitalizations, mainly in children under 2 years of age. Hospitalization affects the caregivers’ quality of life (QoL).
August Wrotek+2 more
doaj +1 more source
Quality-Adjusted Life-Years without Constant Proportionality [PDF]
A quality-adjusted life-year is a common unit of measurement in health valuation. Under its constant proportionality assumption, the value of a quality-adjusted life span is defined as the product of preference weight and life span.To empirically identify an alternative functional relationship between life span and value by relaxing the constant ...
Peep F. M. Stalmeier+4 more
openaire +2 more sources
Cost effectiveness of telecare management for pain and depression in patients with cancer: results from a randomized trial [PDF]
OBJECTIVE: Pain and depression are prevalent and treatable symptoms among patients with cancer, yet they are often undetected and undertreated. The Indiana Cancer Pain and Depression (INCPAD) trial demonstrated that telecare management can improve pain ...
Cheville, Andrea L.+3 more
core +1 more source
A technique for approximating transition rates from published survival analyses
Background Quality-adjusted-life-years (QALYs) are used to concurrently quantify morbidity and mortality within a single parameter. For this reason, QALYs can facilitate the discussion of risks and benefits during patient counseling regarding treatment ...
Markian A. Pahuta+4 more
doaj +1 more source
Forecasting the Effects of Obesity and Smoking on U.S. Life Expectancy [PDF]
Background: While increases in obesity over the past 30 years have adversely affected population health, there have been concomitant improvements due to reductions in smoking.
Cutler, David M.+2 more
core +1 more source
Cost-Effectiveness of Interferon Beta-1a, Interferon Beta-1b, and Glatiramer Acetate in Newly Diagnosed Non-primary Progressive Multiple Sclerosis [PDF]
ObjectiveTo perform a cost-effectiveness analysis of three immunomodulatory treatments for newly diagnosed nonprimary progressive MS: interferon beta-1a, interferon beta-1b, and glatiramer acetate.MethodsWe developed a state-transition model to estimate ...
Bar-Or, Amit+3 more
core +1 more source
HIV Cure Strategies: How Good Must They Be to Improve on Current Antiretroviral Therapy? [PDF]
Background: We examined efficacy, toxicity, relapse, cost, and quality-of-life thresholds of hypothetical HIV cure interventions that would make them cost-effective compared to life-long antiretroviral therapy (ART).
Berkowitz, Bethany K.+11 more
core +9 more sources