Diffusion Tractography Biomarker for Epilepsy Severity in Children With Drug‐Resistant Epilepsy
ABSTRACT Objective To develop a novel deep‐learning model of clinical DWI tractography that can accurately predict the general assessment of epilepsy severity (GASE) in pediatric drug‐resistant epilepsy (DRE) and test if it can screen diverse neurocognitive impairments identified through neuropsychological assessments.
Jeong‐Won Jeong +7 more
wiley +1 more source
Quality-Adjusted Life-Years Lost Due to COVID-19 Mortality: Methods and Application for The Netherlands. [PDF]
Wouterse B, Ram F, van Baal P.
europepmc +1 more source
PRM29 Comparison of Discrete Discounting and Non-Constant Exponential Discounting Approaches to Calcuate Future Gains in Quality-Adjusted Life-Years [PDF]
Vishvas Garg, Dennis W. Raisch
openalex +1 more source
Using Rasch analysis to form plausible health states amenable to valuation: the development of CORE-6D from CORE-OM in order to elicit preferences for common mental health problems [PDF]
Purpose: To describe a new approach for deriving a preference-based index from a condition specific measure that uses Rasch analysis to develop health states.
Barkham, M +3 more
core +1 more source
ABSTRACT Background Neurodegeneration with brain iron accumulation (NBIA) comprises a genetically and clinically heterogeneous group of rare neurological disorders characterized particularly by iron accumulation in the basal ganglia. To date, 15 genes have been associated with NBIA.
Seda Susgun +95 more
wiley +1 more source
Top Cited Papers in International Psychogeriatrics: 2. Quality Adjusted Life Years in Older Adults With Depressive Symptoms and Chronic Medical Disorders [PDF]
Jürgen Unützer, David Ames
openalex +1 more source
Intensive Medical Care and Cardiovascular Disease Disability Reductions [PDF]
There is little empirical evidence to explain why disability declined among the elderly over the past 20 years. In this paper, we explore the role of improved medical care for cardiovascular disease on health status improvements over time.
David M. Cutler +2 more
core
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin +6 more
wiley +1 more source
Amyotrophic Lateral Sclerosis Prevalence Projection in 2040: A Less Rare Disease
ABSTRACT Objective To project ALS prevalence across multiple countries through 2040, accounting for both population aging and increased survival. Methods Data from the Piemonte and Valle d'Aosta ALS register (PARALS) was used to estimate the trends in incidence and prevalence from 2005 to 2019. Survival trends over this period were also assessed.
Rosario Vasta +18 more
wiley +1 more source
Analysis of Health and Activity Limitation Index (HALex), Its Distribution, andIts Distribution by Income in Japan, 1989 and 1998, [PDF]
It is a widely shared view in the population health field that the future of the analysis of population health lies in the assessment both of the length of life and health-adjusted quality of life, and the parallel examination of the average health and ...
Yasushi Ohkusa, Yukiko Asada
core

