Results 61 to 70 of about 1,397,662 (274)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

DecideNet: Counting Varying Density Crowds Through Attention Guided Detection and Density Estimation

, 2018
In real-world crowd counting applications, the crowd densities vary greatly in spatial and temporal domains. A detection based counting method will estimate crowds accurately in low density scenes, while its reliability in congested areas is downgraded ...
Gao, Chenqiang, Hauptmann, Alexander G., Liu, Jiang, Meng, Deyu   +3 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

No-Reference Quality Assessment for Contrast-Distorted Images

IEEE Access, 2020
Contrast distortion is a common distortion type in the image applications. However, there are still very limited approaches proposed for quantifying the quality of the contrast-distorted images reliably.
Yutao Liu, Xiu Li
doaj   +1 more source

TET-GAN: Text Effects Transfer via Stylization and Destylization

, 2018
Text effects transfer technology automatically makes the text dramatically more impressive. However, previous style transfer methods either study the model for general style, which cannot handle the highly-structured text effects along the glyph, or ...
Guo, Zongming, Liu, Jiaying, Wang, Wenjing, Yang, Shuai   +3 more
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Energy-Aware Frame Rate Selection for Video Coding

IEEE Access
The demand for high-quality, immersive video experiences has necessitated adopting higher frame rates for more realistic scene portrayal. However, there is a growing demand for energy-saving video applications, where temporal downsampling is a crucial ...
Geetha Ramasubbu, Andre Kaup, Christian Herglotz   +2 more
doaj   +1 more source

No-Reference Stereoscopic Image Quality Assessment Using Convolutional Neural Network for Adaptive Feature Extraction

IEEE Access, 2018
The pervasion of 3-D technologies over the years gives rise to the increasing demands of accurate and efficient stereoscopic image quality assessment (SIQA) methods, designed to automatically supervise and optimize 3-D image and video processing systems.
Yong Ding, Ruizhe Deng, Xin Xie, Xiaogang Xu, Yang Zhao, Xiaodong Chen, Andrey S. Krylov   +6 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source