Results 131 to 140 of about 1,021,436 (277)

Sulfur isotope analysis of collagen: Quality controls and proboscidean wetland habitats

Quaternary Environments and Humans
Sulfur isotopes (δ34S values) have significant potential for addressing archaeological, paleontological, and paleoecological research questions.
Jessica Z. Metcalfe, Lauryn E. Eady-Sitar, Ayumi Hyodo, Taylor Belot   +3 more
doaj   +1 more source

Homozygous might be hemizygous: CRISPR/Cas9 editing in iPSCs results in detrimental on-target defects that escape standard quality controls. [PDF]

Stem Cell Reports, 2022
Simkin D, Papakis V, Bustos BI, Ambrosi CM, Ryan SJ, Baru V, Williams LA, Dempsey GT, McManus OB, Landers JE, Lubbe SJ, George AL, Kiskinis E.   +12 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The impact of fish oil fatty-acids on post-prandial vascular reactivity. [PDF]

, 2014
Progressive loss of vascular reactivity and increased vascular tone with age are being increasingly recognised as significant cardiovascular disease (CVD) risk factors.
Mcmanus, Sean
core  

A Novel Phantom and a Dedicated Developed Software for Image Quality Controls in X-Ray Intraoral Devices. [PDF]

J Biomed Phys Eng, 2021
Acri G, Gurgone S, Iovane C, B Romeo M, Borzelli D, Testagrossa B.   +5 more
europepmc   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Report on the quality of the LHCb-Muon four-gap MWPC produced at LNF [PDF]

, 2006
The LNF-LHCb team produced 185 four-gap Multi-Wire Proportional Chambers (MWPC). In this note we report the summary of the results of the panel quality controls and of the measurements performed on the assembled ...
Dané, E, Pinci, D, Sarti, A
core  

Comparison of different preparation techniques of dried blood spot quality controls in newborn screening for congenital adrenal hyperplasia. [PDF]

PLoS One, 2021
Grecsó N, Zádori A, Baráth Á, Galla Z, Rácz G, Bereczki C, Monostori P.   +6 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source