Results 111 to 120 of about 2,296,482 (269)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

The reliability and measurement error of the movement quality assessment for athletes. [PDF]

Front Sports Act Living
Wijekulasuriya GA, Woods CT, Kittel A, Larkin P.   +3 more
europepmc   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

The effect of manuscript characteristics on quality assessment of scientific manuscripts in psychology. [PDF]

PLoS One
Augusteijn HEM, Wicherts JM, Sijtsma K, van Assen MALM.   +3 more
europepmc   +1 more source

Assessing research quality [PDF]

Nature Immunology, 2006
openaire   +2 more sources

Assessing the quality of research [PDF]

Medical Education, 2005
Jill, Morrison, John, Bligh
openaire   +2 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Objective quality assessment for precision functional MRI data. [PDF]

Neuron
Lynch CJ, Chang M, Elbau I, Gordon EM, Laumann TO, Du J, Ladwig Z, Lueckel M, Perez DC, Summerville I, Chou J, Johnson M, Ho C, Manfredi N, Nilchian P, Solomonov N, Goldwaser E, Ng T, Moia S, Caballero-Gaudes C, Downar J, Vila-Rodriguez F, Gregory E, Daskalakis ZJ, Blumberger DM, Kay K, Buchanan DM, Williams N, Bhati MT, Clauss J, Zebley B, Victoria LW, Power JD, Grosenick L, Gunning FM, Liston C.   +35 more
europepmc   +1 more source