Results 201 to 210 of about 6,460,655 (331)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Methods of comprehensive assessment of the quality of lawn coatings

F. V. Tiushkevich, O. E. Khanbabaeva
openalex   +1 more source

The relationship of knowledge of nursing process, value and reinforcement to the quantity and quality of written nursing assessments

, 1982
Ardys Symons
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Diagnosis based image quality assessment and enhancement for low dose CT image. [PDF]

Front Radiol
Nirupama B, Dhevdharsan BS, Shreya Reddy U, Joshan Athanesious J, Kiruthika S.   +4 more
europepmc   +1 more source

Assessment of Pancreatic Cancer Care in the United States Based on Formally Developed Quality Indicators [PDF]

, 2009
Karl Y. Bilimoria, David J. Bentrem, Keith D. Lillemoe, Marina Talamonti, Clifford Y. Ko   +4 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Integrated GIS-machine learning approach to irrigation water quality assessment in coastal aquifers. [PDF]

Sci Rep
Nefla L, Bergal A, Boumaraf W, Gheid S, Bouksiba C, Khammar H, Celico F, Nasri H, Gaagai A, Elsayed S, El-Baki MSA, Attiah AM, Székács A, Saeed O, Gad M.   +14 more
europepmc   +1 more source

Video Quality Assessment and Management in Content Distribution Networks [PDF]

, 2008
Mauthe, Andreas, Mu, Mu
core  

Quality assessment of selected dry and processed beans

, 2019
Hsien-Yu Sharon Hsia
openalex   +1 more source