Results 81 to 90 of about 2,608,159 (318)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The relationship between personal-collaborative motivation profiles and students’ performance in collaborative problem solving

Large-scale Assessments in Education
Collaborative problem solving (CPS), as a twenty-first century skill, is critically important for both living and life-long learning. Motivation in CPS equates to students’ needs to recognize their efforts in collaboration.
Jinming He, Shixiu Ren, Danhui Zhang
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Effects of intensive care unit quality assessment on changes in medical staff in medical institutions and in-hospital mortality

Human Resources for Health
Background Quality assessments are being introduced in many countries to improve the quality of care and maintain acceptable quality levels. In South Korea, various quality assessments are being conducted to improve the quality of care, but there is ...
Seungju Kim, Gui Ok Kim, Syalrom Lee, Yong Uk Kwon   +3 more
doaj   +1 more source

Barriers, facilitators and unmet needs for achieving a good death and enhancing end-of-life care in the Catalan Health System: a qualitative study

BMJ Open
Background and objective A qualitative study was conducted in Catalonia (Spain), incorporating the views and opinions of relatives, healthcare professionals and patients on what they considered a ‘good death’.
Anna Garcia-Altes, Mireia Espallargues, Vicky Serra-Sutton, Luisa Fernández-Giner, Mónica Caldeiro   +4 more
doaj   +1 more source

Quality assessment of user-generated video using camera motion [PDF]

, 2013
With user-generated video (UGV) becoming so popular on theWeb, the availability of a reliable quality assessment (QA) measure of UGV is necessary for improving the users’ quality of experience in videobased application.
Guo, Jinlin, Cathal Gurrin, Frank Hopfgartner, Songyang Lao, Hopfgartner, Frank, Gurrin, Cathal, Jinlin Guo, Zhang, Zhenxing, Zhenxing Zhang, Lao, Songyang   +9 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Towards a Taxonomy of Process Quality Characteristics for Assessment [PDF]

, 2018
Previous assessment of process quality have focused on process capability (i.e. the ability of a process to meet its stated goals). This paper proposes a taxonomy of alternative process quality characteristics based on intrinsic and extrinsic quality ...
Shrestha, Anup, Anup Shrestha
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source