Results 101 to 110 of about 222,384 (292)

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

Aging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

Training-Aware Risk Control for Intensity Modulated Radiation Therapies Quality Assurance with Conformal Prediction [PDF]

arXiv
Measurement quality assurance (QA) practices play a key role in the safe use of Intensity Modulated Radiation Therapies (IMRT) for cancer treatment. These practices have reduced measurement-based IMRT QA failure below 1%. However, these practices are time and labor intensive which can lead to delays in patient care.
arxiv  

Regularization and Hierarchical Prior Distributions for Adjustment with Health Care Claims Data: Rethinking Comorbidity Scores [PDF]

arXiv, 2017
Health care claims data refer to information generated from interactions within health systems. They have been used in health services research for decades to assess effectiveness of interventions, determine the quality of medical care, predict disease prognosis, and monitor population health. While claims data are relatively cheap and ubiquitous, they
arxiv  

Managing HIV/AIDS in Malawi [PDF]

arXiv, 2014
The epidemic of HIV in Malawi started early and at its peak 15% of all adults were infected with HIV. Malawi is a low-income country and the cost of putting all HIV-positive people in Malawi onto ART, expressed as a percentage of the gross domestic product, is the highest in the world.
arxiv  

Productivity and quality-adjusted life years: QALYs, PALYs and beyond [PDF]

We develop a unified framework for the measurement and valuation of health and productivity. Within this framework, we characterize evaluation functions allowing for compromises between the classical quality-adjusted life years (QALYs) and its polar productivity-adjusted life years (PALYs).
arxiv   +1 more source

Geographic Partitioning Techniques for the Anonymization of Health Care Data [PDF]

arXiv, 2015
Hospitals and health care organizations collect large amounts of detailed health care data that is in high demand by researchers. Thus, the possessors of such data are in need of methods that allow for this data to be released without compromising the confidentiality of the individuals to whom it pertains.
arxiv  

Selecting Hospital\'s Key Performance Indicators, Using Analytic Hierarchy Process Technique

Journal of Community Health Research, 2013
Introduction: hospitals performance indicators will help monitoring, evaluation and decision making and therefore must be selected and ranked accurately.
Raana Gholamzadeh Nikjoo, Hossein Jabbari Beyrami, Ali Jannati, Mohammad Asghari Jaafarabadi   +3 more
doaj  

Effects of cardiac motion on dose distribution during stereotactic arrhythmia radioablation treatment: A simulation and phantom study

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Cardiac motion may degrade dose distribution during stereotactic arrhythmia radioablation using the CyberKnife system, a robotic radiosurgery system. This study evaluated the dose distribution changes using a self‐made cardiac dynamic platform that mimics cardiac motion. Methods The cardiac dynamic platform was operated with amplitudes
Takayuki Miyachi, Takeshi Kamomae, Fumitaka Kawabata, Kuniyasu Okudaira, Mariko Kawamura, Shunichi Ishihara, Shinji Naganawa   +6 more
wiley   +1 more source

T2‐weighted imaging of rectal cancer using a 3D fast spin echo sequence with and without deep learning reconstruction: A reader study

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To compare image quality and clinical utility of a T2‐weighted (T2W) 3‐dimensional (3D) fast spin echo (FSE) sequence using deep learning reconstruction (DLR) versus conventional reconstruction for rectal magnetic resonance imaging (MRI).
Dan Nguyen, Sarah Palmquist, Ken‐Pin Hwang, Jingfei Ma, Usama Salem, Jia Sun, Xinzeng Wang, Jong Bum Son, Randy Ernst, Peng Wei, Harmeet Kaur, Nir Stanietzky   +11 more
wiley   +1 more source

Modelling of a double‐scattering proton therapy nozzle using the FLUKA Monte Carlo code and analysis of linear energy transfer in patients treated for prostate cancer

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The dose‐averaged linear energy transfer (LETD) in proton therapy (PT) has in pre‐clinical studies been linked to the relative biological effectiveness (RBE) of protons. Until recently, the most common PT delivery method in prostate cancer has been double‐scattered PT, with LETD only available through dedicated Monte Carlo (MC ...
Rasmus Klitgaard, Lars Fredrik Fjæra, Camilla Hanquist Stokkevåg, Perry Johnson, Mark Artz, Nancy Price Mendenhall, Curtis Bryant, Ludvig Paul Muren   +7 more
wiley   +1 more source