Results 101 to 110 of about 524,263 (307)

Begriffe und Konzepte des Qualitätsmanagements – 4. Auflage

GMS Medizinische Informatik, Biometrie und Epidemiologie, 2018
Quality and safety of healthcare have become key concepts during the last two decades on both national and international levels. In Germany this target of healthcare policy is currently regulated by a cascade of legal requirements and directives: all ...
Sens, Brigitte, Pietsch, Barbara, Fischer, Burkhard, Hart, Dieter, Kahla-Witzsch, Heike Anette, von Friedrichs, Verena, Nothacker, Monika, Paschen, Ulrich, Rath, Sabine, Rode, Susanne, Schneider, Kyra, Schrappe, Matthias   +11 more
doaj   +1 more source

Healthcare quality management in Great Britain and Czech Republic [PDF]

, 2017
Healthcare quality can be defined as the summary of the results achieved in prevention, diagnosis and treatment, based on findings of medical science and practice, or as the degree of excellence of the provided care in relation to a contemporary level of
Briš, Petr, Keclíková, Kristýna, Macuda, Malgorzata, Čermáková, Marie   +3 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Analisis Upaya Rumah Sakit Islam Sultan Agung Kota Semarang sebagai Fasilitas Kesehatan Tingkat Lanjut dalam Penerapan Program Jaminan Kesehatan Nasional Tahun 2014 [PDF]

, 2015
Communities are entitled to the protection of health and the state arranged for the fulfillment of a healthy life. The state develops social assurance system for all people.
Mahmudah, P. N. (Puri), Suryawati, C. (Chriswardani), Wigati, P. A. (Putri)   +2 more
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Measuring tangibility and assurance as determinants of service quality for public health care in South Africa

Acta Commercii, 2007
Purpose: The purpose of this research is to measure service quality offered to patients treated in a government controlled hospital in South Africa. Desig/Methodology/Approach: A service satisfaction survey was conducted amongst patients treated at ...
J. De Jager, T. Du Plooy
doaj   +1 more source

To share or not to share: Publication and quality assurance of research data outputs. A report commissioned by the Research Information Network

, 2008
A study on current practices with respect to data creation, use, sharing and publication in eight research disciplines (systems biology, genomics, astronomy, chemical crystallography, rural economy and land use, classics, climate science and social and ...
Brown, Sheridan, Swan, Alma
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source