Results 91 to 100 of about 1,092,913 (352)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

DEVELOPMENT OF THE LIST OF MAJOR DRAWBACKS AS AN ELEMENT OF STUDY PROGRAMME EVALUATION IN LINE WITH THE ESG 2015 STANDARDS

Неперервна професійна освіта: теорія та практика
The article explores the initial stage in forming a model for establishing the correspondence of study programme evaluation criteria to the key parameters of the Standards and Guidelines for Quality Assurance in the European Higher Education Area (ESG ...
Andrii Butenko, Olena Yeremenko, Oxana Trebenko   +2 more
doaj   +1 more source

Quality of maternal and child health services in Tanzanian primary healthcare: a 2021–2022 star rating review

Reproductive Health
Background Tanzania faces high maternal and infant mortality rates, yet key service quality metrics remain underexamined, limiting targeted improvements. Star Rating Assessment (SRA), introduced in 2015, aims to improve primary health care (PHC) quality,
Erick S. Kinyenje, Martin M. Degeh, Joseph C. Hokororo, Syabo M. Mwaisengela, Ruth R. Ngowi, Omary A. Nassoro, Chrisogone J. German, Radenta P. Bahegwa, Yohanes S. Msigwa, Atuganile Musyani, Laura E. Marandu, Michael Habtu, Jennifer T. Mbise, Habibu Ismail, Janeth Masuma, Faraja Msemwa, Joanita Muruve, Saturini Manangwa, Daudi Msasi, Jimmy Mbelwa, Athman Pembe, Ahmad M. Makuwani, Ntuli A. Kapologwe, Tumaini J. Nagu, Eliudi S. Eliakimu   +24 more
doaj   +1 more source

QUALITY AND QUALITY ASSURANCE IN THE FRESH PRODUCE SECTOR: A CASE STUDY OF EUROPEAN RETAILERS [PDF]

Quality and quality assurance are among the most critical issues facing the fresh produce industry. This paper shows that while quality is widely noted to be an important concept, it is not clearly defined in the literature.
Codron, Jean-Marie, Reardon, Thomas, Sterns, Patricia Aust   +2 more
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Design, development, and optimization of mucoadhesive buccal films of ganaxolone for enhanced bioavailability

Journal of Applied Pharmaceutical Research
Background: CDD disorder affects children mainly during their first three months of life. The buccal route offers advantages over oral administration for ganaxolone by avoiding first-pass metabolism and providing direct systemic absorption.
Onkar Pawar, Rahul Godge, Ganesh Shinde, Kailas Barde, Akshay Vikhe   +4 more
doaj   +1 more source

Stakeholders’ Perspectives on Quality Assurance of Pharmacy Education in the Eastern Mediterranean Region [PDF]

, 2018
Dalia Bajis, Rebekah Moles, Dip Hosp, Betty Chaar   +3 more
openalex   +1 more source

Estyn arrangements for assuring the quality of contracted out inspections : policies and procedures [PDF]

, 2010
"This document represents Estyn’s policy and procedures for assuring the quality of contracted out inspections. The quality assurance policy and procedures outlined in sections 1 to 3 of this document and summarised in appendix 1 apply to all inspectors ...

core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Blue applicability grade index assessment and response surface modelling to synchronous determination of metformin hydrochloride, vildagliptin and dapagliflozin propanediol monohydrate by HPTLC method

Future Journal of Pharmaceutical Sciences
Diabetes mellitus is major chronic disease found in human due to stressful lifestyle and bad food habit. Recently, the Central Drugs Standard Control Organization of India has approved combination of metformin hydrochloride, vildagliptin and ...
Pintu Prajapati, Krutika Patil, Dhrumi Naik, Veera Shakar Pulusu, Anzarul Haque, Mohd Abul Kalam, Shailesh Shah   +6 more
doaj   +1 more source