Results 111 to 120 of about 907,233 (304)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Green analytical chemistry-based spectrophotometric techniques for ternary component analysis of pain relievers

Future Journal of Pharmaceutical Sciences
Background The management of pain presents a significant challenge in healthcare, particularly in cases where conventional therapies prove inadequate.
Thirumalai Arunagiri, Alagammai Ganesan, Vamsi Ravi Kumaran, Bharathraj Masilamani, Kanaka Parvathi Kannaiah, Damodharan Narayanasamy   +5 more
doaj   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source

European food quality policy: the importance of geographical indications, organic certification and food quality insurance schemes in European countries [PDF]

The protection of geographical indications, organic certification and food quality assurance schemes are the cornerstones of European food quality policy.
Becker, Tilman C., Staus, Alexander
core   +1 more source

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source

Quality Assurance [PDF]

Modern Pathology, 2016
openaire   +5 more sources

Use of the Reference Method for Determination of Serum Calcium in a Quality-Assurance Survey [PDF]

, 1975
John F. Pickup, Malcolm J. Jackson, E Margaret Price, M. J. R. Healy, S. S. Brown   +4 more
openalex   +1 more source

Estyn arrangements for assuring the quality of contracted out inspections : policies and procedures [PDF]

, 2010
"This document represents Estyn’s policy and procedures for assuring the quality of contracted out inspections. The quality assurance policy and procedures outlined in sections 1 to 3 of this document and summarised in appendix 1 apply to all inspectors ...

core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

“You Can’t Look for Disparities Where Data Are Missing”: Interviews with Health Plans on Managing Race and Ethnicity Data in the Pursuit of Health Equity

Health Equity
Introduction: Many health plans in the United States are working to address disparities in care by race/ethnicity. A fundamental part of this work involves implementing processes for collecting race/ethnicity data to visualize where there are gaps for ...
Shawn A. Trivette, Keirsha Thompson, Rhea Mundra, Rachel Harrington   +3 more
doaj   +1 more source