Results 61 to 70 of about 1,054,558 (353)

Greenness analysis of stability indicating RP-HPLC method for determination of lobeglitazone sulphate and glimepiride in tablets

Discover Chemistry
The present study focuses on the development and validation of a stability-indicating reversed-phase high-performance liquid chromatography (RP-HPLC) method for the simultaneous quantification of lobeglitazone sulfate (LBG) and glimepiride (GLM) in ...
Aashiya Patel, Aesha Bhalodia, Sonal Desai, Suchi Desai, Yachita Jokhi, Megha Shah   +5 more
doaj   +1 more source

The challenge of producing an EQA for the COVID-19 pandemic

Practical Laboratory Medicine, 2020
The COVID-19 pandemic has changed the clinical medicine landscape. The importance of pathology testing has come to the forefront. Patients or potential patients are dealing directly with laboratories as they line up in carparks or testing staff come to ...
Tony Badrick, Louise Wienholt, Daniel Fone, Derek Holzhauser   +3 more
doaj   +1 more source

Analytical Quality Assurance

, 2010
As we described in Chapter 1, Services are often provisioned within short-term, volatile and highly dynamic (business) processes. These processes are designed in an abstract manner and when instantiated can involve service providers not known of during the design time of the service-based application.
A. Metzger, S. Benbernou, M. Carro, M. Driss, G. Kecskemeti, R. Kazhamiakin, K. Krytikos, MOCCI, ANDREA, DI NITTO, ELISABETTA, B. Wetzstein, F. Silvestri   +10 more
openaire   +3 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Quality comparability analysis on production site change of human coagulation factor Ⅷ

Zhongguo shuxue zazhi
Objective To study the quality comparability of human coagulation factor Ⅷ (FⅧ) produced before and after the change of factory site. Methods A comparative study was carried out on quality quantitative indexes, related impurities and stability data of FⅧ
TIAN Tianli, WANG Hanyu, MA Yiyun, XUE Wei, ZHANG Shengchao, ZHANG Yaoyin, ZHOU Shunbo, ZOU Lingling, CHEN Chuan, DING Yaling   +9 more
doaj   +1 more source

Comprehensive Review of Analytical Methods for Quantifiable Estimation of Gliptins, Including Metformin, in Pharmaceutical and Bulk Dosage Forms [PDF]

E3S Web of Conferences
Insufficient insulin secretion or action leads to diabetes mellitus, causing chronic hyperglycemia and metabolic abnormalities. Metformin is a common medication recommended as first-line treatment for Type 2 DM, aiming to prevent complications and early ...
Dhruv Ashwini P., Vyas Dr. Amit kumar J.
doaj   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Red, green, and blue model assessment and AQbD approach to HPTLC method for concomitant analysis of metformin, pioglitazone, and teneligliptin

Future Journal of Pharmaceutical Sciences
Background The CDSCO of India has authorized a combination of metformin hydrochloride, teneligliptin hydrochloride, and pioglitazone hydrochloride for the treatment of insulin-independent diabetes.
Pintu Prajapati, Pooja Patel, Dhrumi Naik, Anzarul Haque, Shailesh Shah   +4 more
doaj   +1 more source

Weighing the costs: Implementing the SLMTA programme in Zimbabwe using internal versus external facilitators

African Journal of Laboratory Medicine, 2014
Background: In 2010, the Zimbabwe Ministry of Health and Child Welfare (MoHCW) adopted the Strengthening Laboratory Management Toward Accreditation (SLMTA) programme as a tool for laboratory quality systems strengthening.
Edwin Shumba, Phoebe Nzombe, Absolom Mbinda, Raiva Simbi, Douglas Mangwanya, Peter H. Kilmarx, Elizabeth T. Luman, Sibongile N. Zimuto   +7 more
doaj   +1 more source

Quality assurance procedures for V378A matrix resin [PDF]

, 1985
A characterization methodology has been developed on which to base quality assurance procedures for U.S. Polymeric V378A bismaleimide matrix resin. Chemical composition is established by partition reverse phase and size exclusion liquid chromatography ...
Dynes, P. J., Hamermesh, C. L.
core   +1 more source