Results 61 to 70 of about 997,782 (356)

Quality control of the traditional herbs and herbal products: a review

Future Journal of Pharmaceutical Sciences, 2020
Background Herbal medicinal material and product need is increasing, and with this increase in the need, it is very much an essential requirement to maintain the quality of them.
Amruta Balekundri, Vinodhkumar Mannur
doaj   +1 more source

Forced Degradation Studies on Agents of Therapeutic Interest

Medical Sciences Forum, 2022
Chalcones possessing potential anti-Alzheimer’s activity were synthesised in our lab using the Claisen Schmidt reaction. FDS (Forced degradation protocols) protocols in accordance with ICH (International Conference on Harmonization) guidelines were ...
Nikita Pravin Pise, Arati Prabhu, Radhika Raheja   +2 more
doaj   +1 more source

A coiled‐coil domain triggers oligomerization of MmpL10, the mycobacterial transporter of trehalose polyphleate precursor

FEBS Letters, EarlyView.
Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston, Jérôme Feuillard, Aurélie Ancelin, Joséphine Lai‐Kee‐Him, Konstantin Brodolin, Christian Chalut, Pontus Gourdon, Mickaël Blaise   +7 more
wiley   +1 more source

Quality Assurance in Higher Education [PDF]

, 2009
Kualitas telah menjadi isu kritis dalam persaingan modern dewasa ini, dan hal itu telah menjadi beban tugas bagi para manager menengah. Dalam tataran abstrak kualitas telah didefinisikan oleh dua pakar penting bidang kualitas yaitu Joseph Juran dan ...
Nurdin, N. (Nurdin)
core  

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Red, green, and blue model assessment and AQbD approach to HPTLC method for concomitant analysis of metformin, pioglitazone, and teneligliptin

Future Journal of Pharmaceutical Sciences
Background The CDSCO of India has authorized a combination of metformin hydrochloride, teneligliptin hydrochloride, and pioglitazone hydrochloride for the treatment of insulin-independent diabetes.
Pintu Prajapati, Pooja Patel, Dhrumi Naik, Anzarul Haque, Shailesh Shah   +4 more
doaj   +1 more source

Client Empowerment and Quality Assurance [PDF]

, 2008
Measurements of quality in social care services in the UK have generally been concerned with regularly measuring performance in terms of Quality Indicators or Best Value reports.
Dowling, Monica
core  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

Molecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu, Fenglin Shen, Yang Liu, Ziqing Zhong, Yongling Chen, Zhiyuan Xia, Cuiju Mo, Hongxiu Yu   +7 more
wiley   +1 more source

Design, development, and optimization of mucoadhesive buccal films of ganaxolone for enhanced bioavailability

Journal of Applied Pharmaceutical Research
Background: CDD disorder affects children mainly during their first three months of life. The buccal route offers advantages over oral administration for ganaxolone by avoiding first-pass metabolism and providing direct systemic absorption.
Onkar Pawar, Rahul Godge, Ganesh Shinde, Kailas Barde, Akshay Vikhe   +4 more
doaj   +1 more source