Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Internet of Things: Current Challenges in the Quality Assurance and Testing Methods
Contemporary development of the Internet of Things (IoT) technology brings a number of challenges in the Quality Assurance area. Current issues related to security, user's privacy, the reliability of the service, interoperability, and integration are ...
A Al-Fuqaha +18 more
core +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Development of a novel delivery quality assurance system based on simultaneous verification of dose distribution and binary multi-leaf collimator opening in helical tomotherapy. [PDF]
Tanaka Y +4 more
europepmc +1 more source
Mentoring in the Lifelong Learning Sector: a critical heuristic account [PDF]
This paper explores a heuristic (‘allowing people to learn for themselves’ [Allen, 2004: p. 654]) mentoring case involving an Advanced Practitioner (AP) tasked with the role of mentoring a trainee PGCE teacher who had received a grade 4 (unsatisfactory)
Rushton, Ian
core +2 more sources
Providing a quality service has become a must in the library and information science sector today. The readers expect an effective and efficient library service from the library staff.
H. Dissanayake
semanticscholar +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Traceability and Assurance Protocols in the Global Food System [PDF]
In the 21st century, the food supply chain has become a complex, interconnected system with strategies that are aimed at creating improved products to satisfy consumers' demand for safer foods.
Bolotova, Yuliya +3 more
core +1 more source
Система внутрішнього забезпечення якості вищої освіти: досвід Республіки Польща [PDF]
The article analyzes the higher education institutions activities of the Republic of Poland in order to identify the perspective directions of the use of Polish experience in quality assurance in Ukraine.
Грищук, Юлія Володимирівна
core
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source

