Results 81 to 90 of about 22,636,583 (251)

Quality assurance during system/product development [PDF]

, 1990
Bibliography: leaves 85-86.This thesis discusses the need for and requirements of quality assurance during development of systems and products. Quality Assurance is necessary during the acquisition programme to verify that the deliverable end products ...
Schultz, Richard Wilhelm
core   +1 more source

CGIAR System Internal Audit Function Quality Assurance and Improvements Program

, 2018
Purpose: This document outlines a Quality Assurance and Improvements Program (QAIP) which is designed to provide reasonable assurance that the CGIAR System Internal Audit Function: Performs its work in accordance with its Terms of References, the ...
CGIAR System Organization
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

QUALITY AND QUALITY ASSURANCE IN THE FRESH PRODUCE SECTOR: A CASE STUDY OF EUROPEAN RETAILERS [PDF]

Quality and quality assurance are among the most critical issues facing the fresh produce industry. This paper shows that while quality is widely noted to be an important concept, it is not clearly defined in the literature.
Codron, Jean-Marie, Reardon, Thomas, Sterns, Patricia Aust   +2 more
core  

QUALITY STANDARDS FOR DISTANCE LEARNING IN HIGHER EDUCATION: A COMPARATIVE ANALYSIS OF CANADIAN AND RUSSIAN PRACTICES

Образование и наука, 2015
The aim of the investigation is to perform comparative analysis of the quality assessment and policies of quality assurance in postsecondary education in Canada and Russian Federation.Methods.
Natalia V. Buhanova, Konstantin V. Kuz’min, Larisa E. Petrova, Sergey A. Chemezov   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

System assurance: beyond detecting vulnerabilities

, 2010
In this day of frequent acquisitions and perpetual application integrations, systems are often an amalgamation of multiple programming languages and runtime platforms using new and legacy content. Systems of such mixed origins are increasingly vulnerable
Campara, Djenana, Campara, Djenana., Mansourov, Nikolai., Mansourov, Nikolai   +3 more
core  

Quality assurance in stereotactic radiosurgery/radiotherapy according to DIN 6875-1 [PDF]

, 2004
The new DIN (' Deutsche Industrie- Norm') 6875- 1, which is currently being finalised, deals with quality assurance ( QA) criteria and tests methods for linear accelerator and Gamma Knife stereotactic radiosurgery/ radiotherapy including treatment ...
Wolff, R., Mack, A., Rieker, M., Mack, G., Scheib, S., Czempiel, H., Gianolini, S., Wowra, B., Weltz, D., Seifert, V., Lomax, N. J., Kreiner, H. J., Muacevic, A., Böttcher, H. D.   +13 more
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source