Results 161 to 170 of about 7,312,830 (305)

Effect of Formulation and Process Variables on the Stability and Quality Attributes of Digoxin Formulations. [PDF]

Pharmaceuticals (Basel)
Shaikh R, Dongala BP, Pansare SJ, Thota SK, Nutan MTH, Offili TU, Khan MA, Rahman Z.   +7 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Oregon DEQ air quality monitoring ... annual report

, 1998
Covers OCLC #42360784, OCLC #1024315364, OCLC #12281291921998-Title from cover.Mode of access: Internet from the Oregon Government Publications Collection.This archived document is maintained by the Oregon State Library as part of the Oregon Documents ...

core  

Foam-Mat Drying of Camel Milk: Evaluation of Physicochemical Quality Attributes and Powder Properties. [PDF]

Food Sci Nutr
Podine MA, Nejatian M, Fathi M, Taghdir M, Miri NY.   +4 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

A product control framework for extracellular vesicle therapeutics: Quality attributes, stability, analytical procedures, and biodistribution. [PDF]

Int J Pharm X
Moon H, Jung SH, Bae S, Bae G, Lee A, Na JH, Kim JH, Choi JU, Lee S.   +8 more
europepmc   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

The quality turn in South Africa: insights from a comprehensive investigation into the food quality behaviours, perceptions and knowledge of South African consumers with a focus on middle and upper socioeconomic groups [PDF]

Internationally, alternative food quality movements have given rise to a quality turn from the mass consumption model toward an increasing qualitative differentiation of products and demand (Allaire, 2002).
Vermeulen, Hester, Bienabe, Estelle
core  

Effects of Sodium Alginate on the Quality Attributes of Wet Instant Starch Noodle Cakes: From a Multi-Scale Perspective. [PDF]

Foods
Zhang H, Zhang L, Li S, Yang S, Liang Y, Zeng X, Gao F.   +6 more
europepmc   +1 more source