Results 161 to 170 of about 2,964,010 (315)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Influence of input inductance of mains supplying frequency-controlled drive on power quality

, 2012
Ilya Avdeev, Ольга Владимировна Немыкина, А. N. Klymko, V.L. Prihno, V. V. Baranets   +4 more
openalex   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Quality control of actinium-225 and ²²⁵Ac-radiopharmaceuticals: Francium-221 to be or not to be? [PDF]

EJNMMI Radiopharm Chem
Toro-Gonzalez M, Wheeless L, Tangadanchu VKR, Hawkins C, Provo S, Smith W, Hommen M, DeVries D, Harvey J, Drum T, Abou DS.   +10 more
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Developing strategies and quality control in the Ageing and Brain Working Study in ELSA-Brasil. [PDF]

Rev Saude Publica
Quidim AVL, Beuttler R, Eloi HM, Otaduy MCG, Lima Júnior JGA, Teixeira MM, Dardis CELM, Chaim KT, Conforto AB, Leite CDC, Rimkus CM, Suemoto CK, Souza AG, Santos IS, Lotufo PA, Benseñor IJM, Goulart AC.   +16 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Dietary Protein Restriction Ameliorates Cardiac Inflammaging via AMPK-ULK1-Mediated Mitochondrial Quality Control. [PDF]

Aging Cell
Dantas WS, Zunica ERM, Heintz EC, Hoppel CL, Hill CM, Morrison CD, Axelrod CL, Davuluri G, Kirwan JP.   +8 more
europepmc   +1 more source

Quality Control in Crowdsourced Object Segmentation

, 2015
Ferran Cabezas, Aurélie Carlier, Vincent Charvillat, Amaia Salvador, Xavier Giró-i-Nieto   +4 more
openalex   +2 more sources

Prognostic factors for predicting health-related quality of life after intramedullary nailing of tibial fractures: a randomized controlled trial

, 2021
Sheila Sprague, Diane Heels‐Ansdell, Sofia Bzovsky, Radovan Zdero, Mohit Bhandari, M.F. Swiontkowski, Paul Tornetta, David Sanders, Emil H. Schemitsch   +8 more
openalex   +1 more source