Results 41 to 50 of about 3,032,107 (315)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Avian influenza virus surveillance in migratory birds in Egypt revealed a novel reassortant H6N2 subtype

Avian Research, 2019
Background Avian influenza viruses (AIVs) have been identified from more than 100 different species of wild birds around the globe. Wild migratory birds can act as potential spreaders for AIVs to domestic birds between different countries.
Ali M. Zanaty, Ahmed M. Erfan, Wessam H. Mady, Fatma Amer, Ahmed A. Nour, Neveen Rabie, Mohamed Samy, Abdullah A. Selim, Wafaa M. M. Hassan, Mahmoud M. Naguib   +9 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Nutritional Potential of Ziziphus lotus (L.) Lam. Almonds as Compared to Some Oilseeds from Morocco: Evidence from Proximate Composition, Mineral Profiling, and Oil Physicochemical Traits

Journal of Food Quality
Nowadays, there is a great interest in the search for new sources of vegetable oils, natural bioactive compounds, and essential nutrients for human health. Oleaginous fruits and seeds are a good source of nutrients such as oil, carbohydrates, fatty acids,
Hasna Ait Bouzid, Laila Bijla, Mohamed Ibourki, Abderrahim Asbbane, El Hassan Sakar, Jamal Koubachi, Said Gharby   +6 more
doaj   +1 more source

Methodology of forming a model of diagnosis-related groups for cases of medical care using surgery performed by laparoscopic access

Фармакоэкономика
Background. A wide range of endosurgical treatment methods in various medical care profiles and the need for uniformity of calculations required developing a unified approach to the formation of diagnosis-related groups (DRGs) for cases of surgical ...
I. A. Zheleznyakova, O. A. Volkova, E. I. Rumiantseva, I. A. Mikhailov, D. V. Fedyaev, A. V. Zuev, O. S. Plakhotnik, G. V. Trifonova, T. S. Vakhrusheva, E. S. Samsonova, V. V. Omelyanovskiy   +10 more
doaj   +1 more source

Preliminary investigation of the possibility for implementation of modified pharmacopoeial HPLC methods for quality control of metronidazole and ciprofloxacin in medicinal products used in veterinary medicine [PDF]

Macedonian Veterinary Review, 2015
Quality control of veterinary medicine products containing two different frequently used antibiotics metronidazole and ciprofloxacin hydrochloride, was considered and performed, using modified pharmacopoeial HPLC methods.
Marjan Piponski, Tanja Bakovska, Marina Naumoska, , Tatjana Rusevska, Gordana Trendovska Serafimovska, Hristina Andonoska   +5 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Standard operating procedure and quality control standards for age-related cataract in Guangdong Province

Yanke Xuebao
Age-related cataract is the leading blinding eye disease in the world, and surgery is the only effective treatment. The good recovery of vision after cataract surgery depends not only on the patients’ ocular conditions but also on the surgical technique ...
Group Standards Team of SOP and Quality Control Standards for Age-related Cataract in Guangdong Province
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source