Results 41 to 50 of about 8,631,090 (300)

Conceptual quality modelling and integrated control of combined urban drainage system [PDF]

open access: yes, 2017
This paper presents the first results of conceptual quality modelling approach oriented to the integrated real-time control (RTC) strategy for urban drainage networks (UDN) and wastewater treatment plants (WWTP) developed in the European project LIFE ...
Cembrano Gennari, Gabriela   +8 more
core  

Control of Multiple Remote Servers for Quality-Fair Delivery of Multimedia Contents [PDF]

open access: yes, 2014
This paper proposes a control scheme for the quality-fair delivery of several encoded video streams to mobile users sharing a common wireless resource. Video quality fairness, as well as similar delivery delays are targeted among streams.
Changuel, Nesrine   +2 more
core   +2 more sources

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

open access: yesFEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling   +4 more
wiley   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Robust scheduled control of longitudinal flight with handling quality satisfaction [PDF]

open access: yes, 2011
Classic flight control systems are still widely used in the industry because of acquired experience and good understanding of their structure. Nevertheless, with more stringent constraints, it becomes difficult to easily fulfil all the criteria with ...
Akhrif, Ouassima   +3 more
core   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

Pengendalian Kualitas Pada Produksi Cpo Dengan Analisis Biaya Kualitas Di PT Sriwijaya Palm Oil Palembang [PDF]

open access: yes, 2008
Growth of world industry influence high competition inter company, in this phenomenon PT Sriwijaya Palm Oil Palembang also maintain CPO can resulting can accepted at market, so company side must be able make a good quality product, fir that process bad ...
Robiah, Hafiatur
core  

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