Results 121 to 130 of about 2,501,483 (344)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

All-optical pulse reshaping and retiming systems incorporating pulse shaping fiber Bragg grating

open access: yes, 2006
This paper demonstrates two optical pulse retiming and reshaping systems incorporating superstructured fiber Bragg gratings (SSFBGs) as pulse shaping elements.
Ibsen, M.   +3 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Quality improvement: Reducing real-time inventory errors through quality control circles

open access: yesAFRICAN JOURNAL OF BUSINESS MANAGEMENT, 2011
In recent years, with improving living standards in China and people’s enhanced awareness of self-protection, the requirements of medical services have been raised which has seen medical complications such as medication errors rise. To prevent medication errors, hospital pharmacies must improve their technical standards, the service process and the ...
openaire   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

品管圈降低卒中患者住院期间便秘发生率的应用研究 Application of Quality Control Circle in Reducing the Incidence of Constipation in In-hospital Stroke Patients

open access: yesZhongguo cuzhong zazhi, 2019
【摘要】 目的 探讨品管圈活动在降低卒中患者住院期间便秘发生率中的应用及维持效果。 方法 在山东大学附属省立医院神经内科开展品管圈活动,针对神经内科住院卒中患者便秘发生率高的原因进行查检、分析及改进,改进措施实施一个月后,对实施品管圈活动前后卒中患者便秘发生率进行比较。半年后将改善措施推广至保健神经内科,比较实施推广一个月后保健神经内科卒中患者便秘发生率的变化。 结果 改善前调查神经内科170例缺血性卒中患者,改善后调查142例缺血性卒中患者,神经内科卒中患者便秘发生率由改善前的67.64 ...
陈霞,侯晓红,李敏,杜艳,殷霞丽,崔新,张振美,宋梅,杨丽娟
doaj   +1 more source

Impact of a quality control circle on the incidence of catheter-associated urinary tract infection: An interrupted time series analysis [PDF]

open access: hybrid, 2020
Xiao Zhong   +8 more
openalex   +1 more source

Proper Motions and CCD-photometry of Stars in the Region of the Open Cluster Trumpler 2

open access: yes, 2005
The results of the complex study of galactic open cluster Trumpler 2 are presented. In order to obtain the proper motions the positions of 2600 stars up to the limit magnitude B ~ 16.25 mag in the area 80x80 arcmin around the cluster were measured on 6 ...
D. L. Gorshanov   +4 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

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