Results 151 to 160 of about 815,060 (335)

Quality Control Indicators (QCIs) for transurethral resections of bladder tumors: Correlation of QCIs with clinical outcome in a Belgian multi-center prospective registry

, 2020
Tim Muilwijk, Murat Akand, Yannic Raskin, Cedric Jorissen, Lorenz Vanhoucke, Kathy Vander Eeckt, Siska Van Bruwaene, Ben Van Cleynenbreugel, Steven Joniau, F. Van Der Aa   +9 more
openalex   +1 more source

TRPM4 contributes to cell death in prostate cancer tumor spheroids, and to extravasation and metastasis in a zebrafish xenograft model system

Molecular Oncology, EarlyView.
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen, Saurav Subedi, Federico La Manna, Sofia Jarrin, Irida Papapostolou, Marianna Kruithof‐de Julio, Christine Peinelt   +6 more
wiley   +1 more source

LLMs & XAI for Water Sustainability: Seasonal Water Quality Prediction with LIME Explainable AI and a RAG-based Chatbot for Insights [PDF]

arXiv
Ensuring safe water supplies requires effective water quality monitoring, especially in developing countries like Nepal, where contamination risks are high. This paper introduces a hybrid deep learning model to predict Nepal's seasonal water quality using a small dataset with multiple water quality parameters.
arxiv  

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

Molecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti, Shingo Inagaki, Tuyen Thuy Bich Ho, Akihiro Seki, Keiko Yoshida, Kosuke Satomura, Yoshio Sakai, Shuichi Kaneko, Taro Yamashita   +8 more
wiley   +1 more source

Reinvestigating the R2 Indicator: Achieving Pareto Compliance by Integration [PDF]

arXiv
In multi-objective optimization, set-based quality indicators are a cornerstone of benchmarking and performance assessment. They capture the quality of a set of trade-off solutions by reducing it to a scalar number. One of the most commonly used set-based metrics is the R2 indicator, which describes the expected utility of a solution set to a decision ...
arxiv  

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Uwarunkowania zaburzeń snu u kobiet stosujących hormonalną terapię zastępczą i niestosujących hormonalnej terapii zastępczej

Menopause Review, 2010
Symptoms accompanying the changes occurring in a female organism in the climacteric period constitutemore frequently a major health-related problem and via its influence on the quality of life, they also becomesocial-related problems concerning many ...
Maciej Wilczak, Dariusz Samulak, Ewa Mojs, Magdalena Monika Michalska, Łukasz Kaczmarek   +4 more
doaj  

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

THE EFFECTS OF ECONOMIC SANCTIONS ON THE CONTROL OF FOOD QUALITY INDICATORS IN TERMS OF IMPORT SUBSTITUTION

, 2016
D.D. Timershin, A.G. Leu, А. А. Дерканосова, Mohammad Ali Shariati   +3 more
openalex   +1 more source

Clinical significance of stratifying prostate cancer patients through specific circulating genes

Molecular Oncology, EarlyView.
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian, Edouard Jarry, Arynne Santos, Quentin Vesval, Lucie Hamel, Rafael Sanchez‐Salas, Alexis Rompré‐Brodeur, Wassim Kassouf, Raghu Rajan, Fadi Brimo, Marie Duclos, Armen Aprikian, Simone Chevalier   +12 more
wiley   +1 more source