Results 151 to 160 of about 467,464 (312)

Modelling and dynamic optimisation of quality indicator profiles during drying

open access: yes, 2006
Food properties change during processing, causing an altered quality experience by the consumer. Apart from quality considerations, also economic and environmental aspects are important in industry.
Quirijns, E.J.
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Comparison between phantoms for quality control in xeromammography

open access: yes, 1987
An indicator of operating technique (phantom) is very useful for quality control in diagnostic radiology. We tested experimentally that the "Random Phantom" is the most suitable between those commercially available for xeromammography.
GAMBACCINI, Mauro   +4 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Determinants of Dietary Quality: Evidence from Bangladesh

open access: yes
Whereas a large number of empirical studies have been devoted to analyzing consumer demand for dietary energy (or dietary quantity), much less attention has been paid to the demand for dietary quality, an equally important aspect of food security.
Rashid, Dewan Arif   +2 more
core  

Operational quality control for hyperspectral data

open access: yes, 2010
This paper provides a brief overview of ongoing activities at DLR in the field of data quality control. For airborne hyperspectral sensors the current status of Quality Indicator harmonization within the EUFAR project is given.
Schneider, Mathias   +5 more
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Impact of quality control indicator system management program on neoadjuvant and adjuvant therapies for breast cancer: a comparative analysis. [PDF]

open access: yesFront Oncol
Xu S   +14 more
europepmc   +1 more source

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