Results 191 to 200 of about 815,060 (335)

A systematic review on quality indicators for tight glycaemic control in critically ill patients: need for an unambiguous indicator reference subset [PDF]

, 2008
Saeid Eslami, Nicolette F. de Keizer, Evert de Jonge, Marcus J. Schultz, Ameen Abu‐Hanna   +4 more
openalex   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Digital transformation and the choice of management control modes in enterprise groups. [PDF]

PLoS One
Li J, Zhang X.
europepmc   +1 more source

Analysis of Quality Differences in Radix Dipsaci before and after Processing with Salt Based on Quantitative Control of HPLC Multi-Indicator Components Combined with Chemometrics [PDF]

Hangsha Wu, Yue Lv, Rui Tang, Mingfang Zhao, Yafei Li, Feiyang Wei, Changyu Li, Weihong Ge, Weifeng Du   +8 more
openalex   +1 more source

Application of process capability indices to quality control in a clinical chemistry laboratory [PDF]

Clinical Chemistry, 1996
John R. Burnett, Doug Chesher, Gabe Hegedus, Leslie Burnett, G Costaganna   +4 more
openaire   +3 more sources

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

The impact of air pollution on the settlement intention of the floating population--Empirical evidence from China. [PDF]

Sci Rep
Cao D, Xu X, Guo C, Liao Y.
europepmc   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

The impact of carbon information disclosure on corporate green technology innovation in the context of "dual carbon"-- Based on data from heavily polluting industries. [PDF]

PLoS One
Chao L, Hu R, Shi B, Jin X.
europepmc   +1 more source

Development of the model of external control of quality indicators of electronic courses [PDF]

Б. М. Шифрин, Igor Eliseev, Viktoriia Sokolova, Sergey Voinash, Ramil Zagidullin, Stanislav Akhmetshin, Sergey Meshkov   +6 more
openalex   +1 more source