Results 201 to 210 of about 3,714,471 (406)

Quality Control Indicators (QCIs) for transurethral resections of bladder tumors: Correlation of QCIs with clinical outcome in a Belgian multi-center prospective registry

, 2020
Tim Muilwijk, Murat Akand, Yannic Raskin, Cedric Jorissen, Lorenz Vanhoucke, Kathy Vander Eeckt, Siska Van Bruwaene, Ben Van Cleynenbreugel, Steven Joniau, F. Van Der Aa   +9 more
openalex   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Toward an Improved Wind Quality Control for RapidScat

IEEE Transactions on Geoscience and Remote Sensing, 2017
Wenming Lin, M. Portabella
semanticscholar   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

LLMs & XAI for Water Sustainability: Seasonal Water Quality Prediction with LIME Explainable AI and a RAG-based Chatbot for Insights [PDF]

arXiv
Ensuring safe water supplies requires effective water quality monitoring, especially in developing countries like Nepal, where contamination risks are high. This paper introduces a hybrid deep learning model to predict Nepal's seasonal water quality using a small dataset with multiple water quality parameters.
arxiv  

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Reinvestigating the R2 Indicator: Achieving Pareto Compliance by Integration [PDF]

arXiv
In multi-objective optimization, set-based quality indicators are a cornerstone of benchmarking and performance assessment. They capture the quality of a set of trade-off solutions by reducing it to a scalar number. One of the most commonly used set-based metrics is the R2 indicator, which describes the expected utility of a solution set to a decision ...
arxiv  

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Uwarunkowania zaburzeń snu u kobiet stosujących hormonalną terapię zastępczą i niestosujących hormonalnej terapii zastępczej

Menopause Review, 2010
Symptoms accompanying the changes occurring in a female organism in the climacteric period constitutemore frequently a major health-related problem and via its influence on the quality of life, they also becomesocial-related problems concerning many ...
Maciej Wilczak, Dariusz Samulak, Ewa Mojs, Magdalena Monika Michalska, Łukasz Kaczmarek   +4 more
doaj  

THE EFFECTS OF ECONOMIC SANCTIONS ON THE CONTROL OF FOOD QUALITY INDICATORS IN TERMS OF IMPORT SUBSTITUTION

, 2016
D.D. Timershin, A.G. Leu, А. А. Дерканосова, Mohammad Ali Shariati   +3 more
openalex   +1 more source