Results 121 to 130 of about 2,862,737 (350)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Effects of control laws and relaxed static stability on vertical ride quality of flexible aircraft [PDF]

open access: yes
State variable techniques are utilized to generate the RMS vertical load factors for the B-52H and B-1 bombers at low level, mission critical, cruise conditions.
Hinsdale, A. J.   +3 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Evaluation of Turnaround Time for Serum Electrolytes and Troponin I in a Clinical Chemistry Laboratory: A Retrospective Observational Study

open access: yesLife and Science
Objective: The purpose of this research was to assess the turnaround time (TAT) of the clinical chemistry laboratory for serum electrolytes and Troponin I. Study Design: Retrospective observational study.
Tahseen Kazmi   +4 more
doaj   +1 more source

Quality Control of Steel Reinforcement Works For Contractors [PDF]

open access: gold, 2021
Putri Lynna A. Luthan   +2 more
openalex   +1 more source

Three-City Air Study [PDF]

open access: yes
This study analyzes the local regulatory and non-regulatory determinants of ambient air quality in Allegheny, Baltimore, and Cuyahoga Counties over the period 1972-1992.
Powell, Mark
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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