Results 111 to 120 of about 478,960 (314)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Coming back for more: factors linked to higher participation among Veterans with chronic pain in an innovative VA-YMCA wellness clinic

open access: yesBMJ Open Quality
In 2019, the Indianapolis VA developed a Wellness Clinic in partnership with the Young Men’s Christian Associations (YMCA) to comprehensively address Veterans’ chronic pain.
Laura J Myers   +5 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Governor's Watershed Enhancement Board

open access: yes, 1991
An overview of the efforts to improve the quality of Oregon's watersheds.produced by Allied Video Productions.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Studio-Quality Speech Enhancement

open access: yes, 2022
Modern speech content such as podcasts, video narrations, and audiobooks typically requires high-quality audio to support a strong sense of presence and a pleasant listening experience.
Su, Jiaqi
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Oregon plan for salmon and watersheds

open access: yes, 1999
Guidebook -- Chapter 14 addendum."The Oregon Plan for Salmon and Watersheds [logo].""July 1999."This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Creating Cultures of Enhancement: Programme Leader or Programme Manager?

open access: yes, 2020
This short paper by Dr Kimberly Wilder-Davis from University of Glasgow explores the role of the programme leader in building a culture of quality enhancement within their wider programme ...
Wilder-Davis, Kimberly
core  

Analysis of cultivated land degradation in southern China: diagnostics, drivers, and restoration solutions

open access: yesFrontiers in Plant Science
IntroductionCultivated land quality degradation is a critical challenge to food security, requiring effective nature-based restoration strategies based on comprehensive assessments of land quality.
Yanqing Liao   +16 more
doaj   +1 more source

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