Results 191 to 200 of about 14,715,407 (389)

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

The impact of the COVID-19 pandemic on the surgical care continuum in Ethiopia: a national survey

BMC Health Services Research
Background The COVID-19 pandemic severely affected social welfare, the economy, and global health, making delivering even the essential health service impossible.
Amare Hailekiros Gebregzi, Berhane Redae Meshesha, Hassen Mohammed Beshir, Desalegn Bekele Taye, Fitalew Dagnew, Manuel K. Sibhatu, Amanuel Sisay Endeshaw, Fantahun Tarekegn Kumie   +7 more
doaj   +1 more source

Analysis of Yield-Determining Process and Its Application to Yield-Prediction and Culture Improvement of Lowland Rice : CIX. Effects of nitrogen top-dressing at full heading stage on lodging resistance, root activity, yield and kernel quality

, 1972
Akio MATSUZAKI, Seizo Matsushima, Toyoo Tomita, Esho Katsuki   +3 more
openalex   +2 more sources

Total quality management: The key to business improvement [PDF]

, 1991

openalex   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Researches Regarding the Use of Silver and Screen Printed Electrodes to the Improvement of the Drinking Water Quality from Rural Areas

, 1970
Alexandru Cristea
openalex   +2 more sources

Quality Assessment and Improvement for Dose‐Response Models. Some Effects of Study Weaknesses on Study Findings. “C'est Magnifique?”, by Donald E. Herbert [PDF]

, 1994
David Jette
openalex   +1 more source

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

Imprinting, methylation, and expression characterization of the maize ETHYLENE-INSENSITIVE 2-like gene

Crop Journal, 2019
The endosperm plays essential roles in embryogenesis and seed germination and provides abundant resources for human food and industrial products. Identification of genes regulating the development of the endosperm and elucidation of their functions is of
Xiupeng Mei, Ping Li, Lu Wang, Chaoxian Liu, Lian Zhou, Chunyan Li, Yilin Cai   +6 more
doaj  

Improvement of Green Tea Quality Using Primary Heating Tsuyukiri Machine for Steamed Tea Leaves in Southern Kyushu

, 1975
Jiro Tatsuno, Toya HANADA, Hideaki KAJIYA, Tetsuya Matsukubo   +3 more
openalex   +2 more sources