Results 221 to 230 of about 12,119,388 (349)

Postoperative mortality is an inadequate quality indicator for lung cancer resection.

Annals of Thoracic Surgery, 2014
Yinin Hu, T. McMurry, Kristen M. Wells, J. Isbell, G. Stukenborg, B. Kozower   +5 more
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Defining Referral for a Kidney Transplant Evaluation as a Quality Indicator: A Population-Based Cohort Study. [PDF]

Can J Kidney Health Dis
Naylor KL, Kim SJ, Luo B, Wang C, Garg AX, Yohanna S, Treleaven D, McKenzie S, Ip J, Cooper R, Rehman N, Knoll G.   +11 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

The Crossmatch-to-Transfusion Ratio as a Quality Indicator for Blood Bank Utilization: A Retrospective Analysis.

J Pharm Bioallied Sci
Bhatt PS, Ghelani SD, Solanki SH.
europepmc   +1 more source

Soil quality indicator-based land productivity modelling for agricultural sustainability. [PDF]

PLoS One
Yousif IAH, Abdel Hamid A, Aldabaa AA, Hassanein SA, Rebouh NY, Mohamed ES, Shokr MS.   +6 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Consensus-based development and practice testing of a generic quality indicator set for parenteral medication administration at home: a RAND appropriateness method study. [PDF]

BMJ Open
Lok-Visser J, Hunneman R, Bekkers CHJ, Filius PMG, Lenferink A, Leeftink G, Maring JG.   +6 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Integration of Hyperspectral Imaging and Deep Learning for Discrimination of Fumigated Lilies and Prediction of Quality Indicator Contents. [PDF]

Foods
Zhang P, Wang Y, Yan B, Wang X, Zhang Z, Wang S, Yang J.   +6 more
europepmc   +1 more source