Results 91 to 100 of about 2,480,610 (358)

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

FEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke, Nils Alexander Lakomek, Georg Groth   +2 more
wiley   +1 more source

QUALITY INDICATORS FOR STROKE PATIENTS AT HOME-BASED CARE SETTING: A REVIEW

Jurnal Kesehatan Komunitas (Journal of Community Health), 2019
Background: One method to identify the level of performance is using quality of care indicators. Even though many quality indicators of health care have been announced, those which specify in home care services are limited in that none of them describe ...
Nur Chayati, Christantie Effendy, Setyopranoto Setyopranoto   +2 more
doaj   +1 more source

Website Quality Indicators for Consumers

Journal of Medical Internet Research, 2005
The rating tool DISCERN was designed for use by consumers without content expertise to evaluate the quality of health information. There is some evidence that DISCERN may be a valid indicator of evidence-based website quality when applied by health professionals.
Griffiths, Kathleen, Christensen, Helen
openaire   +3 more sources

A working model for cytoplasmic assembly of H/ACA snoRNPs

FEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Quality, satisfaction and loyalty indices

Journal of Place Management and Development, 2018
Purpose The main purpose of this research was to develop a universal model to evaluate the perceived value of tourism services and satisfaction with, and loyalty to, destinations from the consumers’ perspective and demonstrated the model’s applicability in this context.
Castillo Canalejo, Ana María, Jimber del Río, Juan Antonio   +1 more
openaire   +4 more sources

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

An integrated approach to assessing the quality of wines sold on Maikop consumer market

Новые технологии
The quality and safety of food products is one of the main priorities of the Russian State policy in the field of nutrition and well-being of the population.Grape wines are a special type of food product; they are alcoholic beverages obtained as a result
L. V. Lunina, Z. T. Tazova, N. T. Siyukhova   +2 more
doaj   +1 more source

Quality indicators applied in a nursing continuing education program of a high complexity university hospital from Brazil: III - training indicator

Bioscience Journal, 2018
The level of knowledge and training of nursing staff has been related to indicators of quality of care in health, although the application of indicators is still rare related to continuing education programs. The aim of this study was to use the training
Clesnan Mendes- Rodrigues, Eliana Borges Silva Pereira, Renata Lemos de Sousa Neto, Fabíola Alves Gomes, Durval Veloso da Silva, Arthur Velloso Antunes, Rosângela de Oliveira Felice, Guilherme Silva Mendonça, Paula Carolina Bejo Wolkers, Teresa Cristina Ferreira Alves, Rayany Cristina de Souza, Dayane Aparecida Cândida Félix   +11 more
doaj   +1 more source

A Framework For Communicating Qualities Of Indicators

, 2003
No abstracts are to be cited without prior reference to the author.There is a growing focus on ecosystem-based indicators and what qualities they need to satisfy. However, the qualities and the characteristics of the already existing indicators vary substantially. Due to both scientific and societal aspects, so will the future indicators.
Hauge, Kjellrun Hiis, Heldal, Hilde Elise, Olsen, Erik, Skjoldal, Hein Rune   +3 more
openaire   +2 more sources

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source