Results 91 to 100 of about 689,967 (262)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
RELIEVE: Revista Electrónica de Investigación y Evaluación Educativa, 2005 The author proposes an array of indicators of the teaching-learning process designed for the daily practice of internal evaluation of a professional training center.
Miguel A. Andrés
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Selection of materials for blast furnace injection using quality indicators
REM: International Engineering JournalThe injection of pulverized materials is a technique used in most of the blast furnaces in the world to reduce coke and charcoal consumption. In addition, injection is one of the main variables of the blast furnace heat control.
Alex Milton Albergaria Campos +2 more
doaj +1 more source
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
GMS Medizinische Informatik, Biometrie und Epidemiologie, 2007 Background: Many hospital rankings rely on the frequency of adverse outcomes and are based on administrative data. In the study presented here, we tried to find out, to what extent available administrative data of German Sickness Funds allow for an ...
Schäfer, Thomas +4 more
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
COMMODITY ASSESSMENT OF THE QUALITY OF SCOTTISH WHISKY AND STUDY OF DEMAND FOR IT
Економіка та суспільствоThe article is devoted to the current issues of determining the key aspects of studying the market and quality of Scotch whiskey. A review of the whiskey market in Ukraine shows that this product is represented in Ukraine in a wide range, and enters the
Наталія Чуприна +2 more
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