Results 241 to 250 of about 9,859,406 (308)

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Quality indicators for palliative care for older people: An umbrella review. [PDF]

Palliat Med
Hutchison A, Spooner A, Parker D, Yates P.   +3 more
europepmc   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

National Trends in Healthcare Quality in Korea: A Multidimensional Assessment Using OECD Health Care Quality Indicators (2008-2023). [PDF]

J Prev Med Public Health
Lee H, Hwang SH, Cho SA, Jung H, Chang Y, Yun J, Cho S, Kim UN, Koo HY, Cho EB, Kim DH, Lee JY.   +11 more
europepmc   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Quality indicators for safe and effective medication use in long-term care facilities: A modified Delphi study. [PDF]

Br J Clin Pharmacol
Gutteridge DS, Javanparast S, Calder AH, Caughey GE, Stafford AC, Peterson GM, Inacio MC, Hibbert PD, Manias E, Hillen JB, Sluggett JK.   +10 more
europepmc   +1 more source

Comparative analysis of quality indicators in two ISO 9001:2015-certified community pharmacies (2020-2025). [PDF]

Farm Comunitarios
Barris-Blundell D, Benítez-Pacheco G, Mercado-Cano MÁ, Hidalgo-Hidalgo MJ, Ismaiel-Bani Almarjeh A.   +4 more
europepmc   +1 more source

Impact of Structured Data Validation on Case Completeness and Key Quality Indicators in the SWISS Implant Registry (SIRIS Spine): A SINGLE-CENTER Audit. [PDF]

Global Spine J
Aghayev E, Farshad M, Jentzsch T.
europepmc   +1 more source

Optimising data visualisation formats for reporting medication-related care quality indicators: residential aged care staff preferences, interpretations and actions. [PDF]

BMJ Open Qual
Meulenbroeks IC, Urwin R, Timothy A, Newell B, Bucknall T, Neupane S, Badgery-Parker T, Seaman K, Westbrook JI.   +8 more
europepmc   +1 more source