Results 41 to 50 of about 1,314,955 (254)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Regional co-variability of spatial and temporal soil moisture–precipitation coupling in North Africa: an observational perspective [PDF]
Hydrology and Earth System Sciences, 2018 The magnitude and sign of soil moisture–precipitation coupling (SMPC) is investigated using a probability-based approach and 10 years of daily microwave satellite data across North Africa at a 1° horizontal scale. Specifically, the co-existence and co-
I. Y. Petrova +4 more
doaj +1 more source
Early warning signals of tipping points in periodically forced systems [PDF]
Earth System Dynamics, 2016 The prospect of finding generic early warning signals of an approaching tipping point in a complex system has generated much interest recently. Existing methods are predicated on a separation of timescales between the system studied and its forcing ...
M. S. Williamson +2 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A study on effect of performing quality management system on organizational productivity [PDF]
Management Science Letters, 2013 The main purpose of article is to survey the effect of Quality Management System (QMS) on organization efficiency based on the concept of change management. The role of top organization management for QMS implementation and change management solutions to
M. M. Movahedi +2 more
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Ekonomia i Prawo, 2013 Rosnące wymogi pacjentów w stosunku do poziomu jakości świadczonych im usług zdrowotnych, a także istniejąca na rynku konkurencja, zmuszają podmioty lecznicze do ciągłego doskonalenia procesów.
Aleksandra Czerw, Urszula Religioni
doaj +1 more source