Results 141 to 150 of about 168,717,297 (239)

Stigma reduction as quality health care: A qualitative study of structural level mechanisms to address stigma. [PDF]

PLoS One
Treloar C, Lenton E, Kirwan A, Douglass C, Nourse G, Farrugia A, Seear K, Watts C, Stoove M, Cama E.   +9 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

From tokenism to youth leadership in child and adolescent mental health research

Public Health Reviews
Sophie Mae Harrington, Paul Louis Fiedler, Katerina Sidiroglou, Nadia Ahmed, Hannah Brunskill, Jennifer Hall, Ledia Lazëri, João Breda   +7 more
doaj   +1 more source

Global quality of care trends for lip and oral cavity cancer: A quality of care index analysis, 1990-2021. [PDF]

Prev Med Rep
Zhang Y, Xu W, Wang H, Mao L, Sun J.
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Impact of Patient Portals on Asthma and Chronic Obstructive Pulmonary Disease-Related Quality-of-Care Outcomes: Systematic Review. [PDF]

Online J Public Health Inform
Kc S, Hopkinson NS, Neves AL, Majeed A, Laverty AA.   +4 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Assessing the quality of care in low- and middle-income countries: a rapid review of the landscape of assessment tools. [PDF]

BMJ Glob Health
Togbenon NDL, Cooper S, Vigan AA, Lokossou SE, Danhoundo R, Agoligan Tometin NJE, Agossou MCU, Dossou RSL, Dossou JP, Criel B, Bello K.   +10 more
europepmc   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Beyond Surgical Technique: Precision, Personalization and Quality of Care in Oral and Maxillofacial Surgery. [PDF]

Medicina (Kaunas)
Aquilanti L, Rappelli G.
europepmc   +1 more source