Results 91 to 100 of about 5,811,138 (314)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Ameliorative Effect of Itaconic Acid/IRG1 Against Endoplasmic Reticulum Stress-Induced Necroptosis in Granulosa Cells via PERK-ATF4-AChE Pathway in Bovine

Cells
The necroptosis of granulosa cells has been proven to be one of the important triggers of follicular atresia, which is an important cause of reduced reproductive capacity in cows.
Xiaorui Yang, Yue Chen, Xinzi Wang, Gaoqing Xu, Hongjie Wang, Xinqi Shu, He Ding, Xin Ma, Jing Guo, Jun Wang, Jing Zhao, Yi Fang, Hongyu Liu, Wenfa Lu   +13 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Early School Leaving by Design—Prevention, Intervention and Compensation—A Policy Analysis of Early School Leaving and Underachievement Interventions in Europe

Education Sciences
The purpose of this paper is to provide a comparative policy analysis of successful strategies that have been implemented across European countries to address early school leaving (ESL) and academic underachievement.
Martin Brown, Joe O’Hara, Sarah Gardezi, Gerry McNamara, John O’Hara, Geraldine French, Grainne McKenna, Aideen Cassidy, Anne Rowan, Michael McNamara   +9 more
doaj   +1 more source

Towards modeling of comprehensive assessment for licensing in higher education [PDF]

, 2013
In the modern society information technologies, services, quality become the determinative factors of success of any business. The questions of quality management are especially relevant in social sphere, since organization oriented on quality of its ...
Cherednichenko, Olga, Liutenko, I., Pylypenko, A., Yanholenko, Olha   +3 more
core  

Fulfilling the Promise of Preschool for All: Insights Into Issues Affecting Access for Selected Immigrant Groups in Chicago [PDF]

, 2009
Presents findings on access to quality early education among small immigrant groups. Outlines policy implications of programs used, knowledge of "Preschool for All," value of preschool education, transportation and enrollment barriers, and other ...
Gina Adams, Marla McDaniel
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Integrated Proteomics and Metabolomics Reveal Spermine Enhances Sperm Freezability via Antioxidant Pathways

Antioxidants
Sperm freezability exhibits marked individual variability, yet the mechanisms remain unclear. Using bulls as the experimental model, we integrated proteomic (sperm) and metabolomic (seminal plasma) analyses of high-freezability (HF) and control (CF ...
Lewei Guo, Zhuoxuan Gu, Bing Wang, Yunuo Wang, Jiaorong Chen, Yitong Li, Qiuju Zheng, Jing Zhao, He Ding, Hongyu Liu, Yi Fang, Jun Wang, Wenfa Lyu   +12 more
doaj   +1 more source

Quality and quantity of education in the process of development. [PDF]

We develop a theory of human capital investment to study through which channels students react to school quality when deciding about their investment in higher education (secondary and above) and how educational quality affects the growth process of an ...
Castelló-Climent, Amparo, Hidalgo-Cabrillana, Ana   +1 more
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source