Closing the Gap: A Research Agenda for the Study of Health Needs among American Indian/Native Hawaiian Transgender Individuals [PDF]
, 2013 Objectives: To explore health research needs of American Indian and Native Hawaiian (AIINH) transgender individuals. Methods: This qualitative study is composed of four focus groups and one informal meeting, totaling 42 AIINH transgender individuals in ...
Jackson, Trudie, Vernon, Irene S
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Is there a Relationship Between HMO Quality of Care and Financial Performance? Evidence from Texas HMOs [PDF]
The profits earned by health insurance companies have been under intense scrutiny by policymakers and the general public. However, attempts to reduce insurance company profits could affect the quality of care that they provide to their enrollees.
Troy Quast
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Density versus quality in health care provision: Using household data to make budgetary choices in Ethiopia [PDF]
Usage of health facilities in Ethiopia is among the lowest in the world; raising usage rates is probably critical for improving health outcomes. The government has diagnosed the principal problem as the lack of primary health facilities and is devoting a
John Mackinnon +2 more
core +3 more sources
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Building quality primary health care development in the new era towards universal health coverage: a Beijing initiative. [PDF]
Glob Health Res Policy, 2023 Ren M +27 more
europepmc +1 more source
Information Accountability Framework for a Trusted Health Care System [PDF]
, 2010 Trusted health care outcomes are patient centric. Requirements to ensure both the quality and sharing of patients’ health records are a key for better clinical decision making.
Iannella, Renato, Sahama, Tony
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Organizational Change Strategies to Support High-Quality Behavioral Health Care for LGBTQ Individuals. [PDF]
Community Ment Health J, 2023 Beverage HN, Herschell AD.
europepmc +1 more source