Results 131 to 140 of about 178,634,582 (237)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Other title: Report from the Health Care Access Improvement Panel

, 2015
application/pdf"2004 Senate Substitute for HB 2912 and House Substitute for SB 12 established the Health Care Access Improvement Program, which uses an annual assessment on inpatient services provided by hospitals to improve and expand health care ...
Health Care Access Improvement Panel (Kan.).
core   +1 more source

Maternal and child health data quality in health care facilities at the Cape Coast Metropolis, Ghana. [PDF]

BMC Health Serv Res, 2022
Lasim OU, Ansah EW, Apaak D.
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Barriers to quality oral health care among elderly (Geriatric) patients in Oyo State. [PDF]

Afr Health Sci
Akinpelu IA, Balogun AO, Adisa AO, Taiwo JO.   +3 more
europepmc   +1 more source

Quality of health care in Primary Care: perspective of people with Diabetes Mellitus. [PDF]

Rev Bras Enferm, 2023
Palasson RR, Paz EPA, Marinho GL, Pinto LFDS, Teston EF, Gomes MA, Souza MHDN, Marcon SS.   +7 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Measuring Quality of Care : A Rasch Validity Analysis of the Good Nursing Care Scale

, 2019
BACKGROUND: Patient-centeredness is emphasized in both health policies and practice, calling for reliable instruments for the evaluation of the quality of nursing care.
Katajisto, Jouko, Leino-Kilpi, Helena, Kottorp, Anders, Stolt, Minna   +3 more
core  

The Connecticut Office of Health Care Access 2004 Small Employer Health Insurance Survey-focus on results /

, 2004
Title from caption.; "Planning tomorrow's health care system today."; "November 2004."; Updates: Employer-sponsored health insurance / Office of Health Care Access. Hartford, CT : Office of Health Care Access, [2001]

core   +1 more source

From tokenism to youth leadership in child and adolescent mental health research

Public Health Reviews
Sophie Mae Harrington, Paul Louis Fiedler, Katerina Sidiroglou, Nadia Ahmed, Hannah Brunskill, Jennifer Hall, Ledia Lazëri, João Breda   +7 more
doaj   +1 more source