Results 241 to 250 of about 4,872,997 (355)

Quality of health care for patients with coronary heart disease and comorbid mental disorders: a prospective cohort study. [PDF]

open access: yesBMC Psychol
Nordmeyer L   +13 more
europepmc   +1 more source

Health-related quality of life among osteoarthritis patients attending primary care clinics of Mangalore city [PDF]

open access: hybrid, 2015
HN Harsha Kumar   +6 more
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Less than one in four mothers get quality intrapartum health care services in Ethiopia. [PDF]

open access: yesSci Rep
Negash WD   +9 more
europepmc   +1 more source

Policies to improve end-of-life decisions in Flemish hospitals: communication, training of health care providers and use of quality assessments [PDF]

open access: gold, 2009
Ina D'haene   +6 more
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

A smartwatch-based CPR feedback device improves chest compression quality among health care professionals and lay rescuers. [PDF]

open access: yesCardiovasc Digit Health J
LaPrad AS   +5 more
europepmc   +1 more source

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