Results 31 to 40 of about 5,128,429 (317)

Repatrierea forței de muncă în contextul pandemiei COVID-19

open access: yesSociologie Românească, 2023
This article aims at providing information about Romanian emigrants in terms of destinations and integration on the labour market at the destination and, at the same time, at tackling with the effects of the COVID-19 pandemic on the mobility and ...
Mălina Voicu   +3 more
doaj   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Effects of Sleep Quality on Quality of Life in Patients with Osteoporosis

open access: yesTürk Osteoporoz Dergisi, 2013
Aim: The purpose of the study was to evaluate sleep quality in osteoporotic individuals, and to determine the associated factors with sleep quality and to investigate the relationship between quality of life and sleep quality Material and Methods: 154 ...
Şule Şahin Onat   +2 more
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Neural calibration of hidden inhomogeneous Markov chains -- Information decompression in life insurance [PDF]

open access: yesarXiv, 2022
Markov chains play a key role in a vast number of areas, including life insurance mathematics. Standard actuarial quantities as the premium value can be interpreted as compressed, lossy information about the underlying Markov process. We introduce a method to reconstruct the underlying Markov chain given collective information of a portfolio of ...
arxiv  

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

A machine learning approach to using Quality-of-Life patient scores in guiding prostate radiation therapy dosing [PDF]

open access: yesarXiv, 2020
Thanks to advancements in diagnosis and treatment, prostate cancer patients have high long-term survival rates. Currently, an important goal is to preserve quality-of-life during and after treatment. The relationship between the radiation a patient receives and the subsequent side effects he experiences is complex and difficult to model or predict ...
arxiv  

AIREX: Neural Network-based Approach for Air Quality Inference in Unmonitored Cities [PDF]

open access: yesarXiv, 2021
Urban air pollution is a major environmental problem affecting human health and quality of life. Monitoring stations have been established to continuously obtain air quality information, but they do not cover all areas. Thus, there are numerous methods for spatially fine-grained air quality inference.
arxiv  

Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase

open access: yesFEBS Letters, EarlyView.
Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka   +6 more
wiley   +1 more source

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