Results 141 to 150 of about 4,051,688 (392)
Equitable Allocation of Healthcare Resources with Fair Cox Models [PDF]
arXiv, 2020 Healthcare programs such as Medicaid provide crucial services to vulnerable populations, but due to limited resources, many of the individuals who need these services the most languish on waiting lists. Survival models, e.g. the Cox proportional hazards model, can potentially improve this situation by predicting individuals' levels of need, which can ...
arxiv
Comparison of symptoms, healthcare utilization, and treatment in diagnosed and undiagnosed individuals with diarrhea-predominant irritable bowel syndrome [PDF]
, 2017 OBJECTIVES: Irritable bowel syndrome (IBS) is a functional bowel disorder characterized by symptoms including abdominal pain and altered bowel function. Up to 75% of individuals with IBS may be undiagnosed.
Chang, Lin, Sayuk, Gregory S, Wolf, Ray
core +2 more sources
FEBS Open Bio, EarlyView.The thermophilic acetogenic model organism Moorella thermoacetica can utilize lactate as substrate. The formation of lactate by reduction of pyruvate is energetically favorable, but the reverse reaction, the oxidation of lactate to pyruvate with NAD+ as electron acceptor is challenging.
Florian P. Rosenbaum, Volker Müller
wiley +1 more source
FEBS Open Bio, EarlyView.FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley +1 more source
Healthcare Utilization and Quality of Life Improvement after Ablation for Paroxysmal AF in Younger and Older Patients [PDF]
, 2017 Background Atrial fibrillation (AF) prevalence increases significantly with age. Little is known about the effect of AF ablation on quality of life and healthcare utilization in the elderly.
Biviano, Angelo B. +9 more
core +1 more source
Identification of inhibitors of the Salmonella FraB deglycase, a drug target
FEBS Open Bio, EarlyView.A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law +6 more
wiley +1 more source
Research Opportunities and Visions for Smart and Pervasive Health [PDF]
arXiv, 2017 Improving the health of the nation's population and increasing the capabilities of the US healthcare system to support diagnosis, treatment, and prevention of disease is a critical national and societal priority. In the past decade, tremendous advances in expanding computing capabilities--sensors, data analytics, networks, advanced imaging, and cyber ...
arxiv
European Respiratory Journal, 2016 Patients with uncontrolled asthma report ongoing symptoms, poor quality-of-life and extensive healthcare use (HCU) and might benefit from management by a specialised severe asthma team.
Akke-Nynke van der Meer +6 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source