Results 181 to 190 of about 168,723,046 (286)

The Double-Edged Nature of Patient-to-Patient Interactions in Digital Healthcare Communities: A Qualitative Study of Patients with Type 2 Diabetes in China. [PDF]

Healthcare (Basel)
Yao T, Liu J, Zhang Y, Cao J, Cao H.
europepmc   +1 more source

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

Advanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang, Zhisheng Xu, Yaou Duan, Yehui Sun, Shiying Wu, Tao Long, Mateusz Durbacz, Li Zhang, Yufen Xiao, Yu‐Chung Pien, Erick D. Guerrero, Zeru Tian, Xu Wang, Pratima Basak, Sumanta Chatterjee, Ning Liu, Xiaochun Li, Eric N. Olson, Daniel J. Siegwart   +18 more
wiley   +1 more source

The QOLA study: psychometric validation of the Quality of Life of Parents of Children with Achondroplasia (QOLA) questionnaire - a multinational study in Germany, Italy, and Portugal. [PDF]

J Patient Rep Outcomes
Adedeji A, Witt S, Maric L, Salomao M, Innig F, Alves I, Provasi C, Sessa M, Mohnike K, Quitmann J.   +9 more
europepmc   +1 more source

Degradable, Skin‐Conformal Nanocomposite‐Based Bioelectronic Patches for High‐Fidelity Electrophysiology and Gesture‐Controlled Robotics

Advanced Functional Materials, EarlyView.
A degradable, skin‐conformal bioelectronic patch combines a starch‐dominated nanocomposite conductor with a gelatin substrate to enable sensitive strain sensing, high‐fidelity electrocardiography, electromyography, electrooculography, and machine‐learning‐assisted gesture control.
Ming Dong, Hongna Yuan, Shubo Liu, Abdulkadir Sanli, Emiliano Bilotti, Han Zhang, Pietro Cataldi, Karin Hing, Oliver Fenwick, Colin J. Humphreys, Dimitrios G. Papageorgiou   +10 more
wiley   +1 more source

Patient-reported outcomes and experience measures in the Community Pharmacy setting: Theoretical and practical framework regarding the PROMs and PREMs. [PDF]

Farm Comunitarios
de la Cuadra-Grande A.
europepmc   +1 more source

Guanosine‐Quadruplex Hydrogels as Dynamic, Mechanically Tunable and Ion Conductive 3D Scaffolds for Cell Culture Applications

Advanced Functional Materials, EarlyView.
Versatile guanosine‐quadruplex (GQ) hydrogels are developed as dynamic biomatrices for cell culture. These scaffolds are fabricated under mild aqueous conditions, present improved stability, tunable mechanical properties within physiological ranges; fibrillar, porous microstructure, ion conductivity, and cytocompatibility.
Neha Thakur, Minye Jin, Pavel Milkin, Deepa Negi, Carla Cofiño Fabres, Hubert Gojzewski, Leonid Ionov, Alla Synytska, Andries van der Meer, Robert Passier, Julieta I. Paez   +10 more
wiley   +1 more source

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu, Xuetong Hao, Yang Zou, Xinglin Chen, Junyan Kong, Chunning Gu, Wenjie Ma, Zhongjun Yang, Huifen Liu, Mengmeng Liu, Xin Tong   +10 more
wiley   +1 more source

Comparing Quality of Life and Well-Being Among Patients with Chronic Diseases. [PDF]

Healthcare (Basel)
Bujang MA, Lai WH, Tiong XT, Khoo SY, Johari F, Kim ARJ, Jee YYH, Tan CHH, Ahmad NFD.   +8 more
europepmc   +1 more source

2024 Aspen Healthcare & Quality of Life Seminar: forging a blueprint for Romania's healthcare transformation

Journal of Medicine and Life
Blidaru, Teodor, Bardoș, Carmen-Mihaela, Arif-Perca, Iulia, Bereș, Sebastian, Bianchi, Ioana, Brîndușan, Adrian, Bundoi, Anca, Codreanu, Codruț, Cotoi, Ovidiu-Simion, Dobre, Adrian-Marius, Drăgoi, Loredana, Dudău, Paul, Furtunescu, Florentina, Grigore, Andreea, Hofmarcher, Thomas, Ifrim, Anca, Iordache, Grațiela, László, Attila, Lupescu, Delia, Maxim, Cristina, Mezinu-Bălan, Larisa, Mihalache, Richard, Nerău, Vlad, Pană, Bogdan, Radu, Cătălin, Sîmbotin, Raluca, Stoea, Iulia, Strilciuc, Ștefan, Ștefan, George, Talpoș, Oana, Trandafir, Iulian, Vâlceanu, Mircea, Dașcă, Laurențiu   +32 more
openaire   +2 more sources

Near‐Infrared Light‐Activated Polydopamine Nanoparticles Conjugated With Transferrin Peptides for Enhanced Brain Accumulation

Advanced Healthcare Materials, EarlyView.
This study demonstrates that Tf‐PDA NPs combine a receptor‐mediated targeting with mild photothermal activation to enhance nanoparticle accumulation in the brain. NIR‐activated Tf‐PDA NPs increase BBB permeability to NPs in vitro and in vivo without inducing cytotoxicity or adverse immune responses.
Rafaela Ferrão, Susana Simões, Paulo Rodrigues‐Santos, Vitor Francisco, Akhilesh Rai, Lino Ferreira   +5 more
wiley   +1 more source