Results 121 to 130 of about 3,611,588 (270)

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

open access: yesFEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law   +6 more
wiley   +1 more source

A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers

open access: yesFEBS Open Bio, EarlyView.
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei   +6 more
wiley   +1 more source

A deep learning approach for predicting the quality of online health expert question-answering services [PDF]

open access: yesarXiv, 2016
Currently, a growing number of health consumers are asking health-related questions online, at any time and from anywhere, which effectively lowers the cost of health care. The most common approach is using online health expert question-answering (HQA) services, as health consumers are more willing to trust answers from professional physicians. However,
arxiv  

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

How to improve hospital admission screening for patients at risk of multidrug-resistant organism carriage: a before-and-after interventional study and cost-effectiveness analysis

open access: yesBMJ Open Quality, 2022
Stéphane Cullati   +6 more
doaj   +1 more source

Distance-Guided GA-Based Approach to Distributed Data-Intensive Web Service Composition [PDF]

open access: yesarXiv, 2019
Distributed computing which uses Web services as fundamental elements, enables high-speed development of software applications through composing many interoperating, distributed, re-usable, and autonomous services. As a fundamental challenge for service developers, service composition must fulfil functional requirements and optimise Quality of Service (
arxiv  

EVALUATING THE SERVICE QUALITY ASSESSMENT OF INDIVIDUALS ATTENDING FITNESS CENTERS IN ANTALYA ACCORDING TO AGE, GENDER AND EDUCATION [PDF]

open access: yesPamukkale Spor Bilimleri Dergisi, 2012
The aim of the study is to evaluate the service quality assessment of individuals attending fitness centers in Antalya, according to gender, age and education variables.
Tennur YERLİSU LAPA, Emrah BAŞTAÇ
doaj  

SAASQUAL: A Quality Model For Evaluating SaaS on The Cloud Computing Environment [PDF]

open access: yesarXiv, 2019
Cloud computing is a Technology that has come out in the last decade and that is transforming the IT industry in huge. The Cloud computing is playing a vital role as a backbone component of the Internet of Things (IoT). In a Cloud Computing scenario, cloud services are accessible via Internet.
arxiv  

CBC Approach for Evaluating Potential SaaS on the Cloud [PDF]

open access: yes(I-TechCON), Jan. 03 -- 04, 2014, 2019
The cloud computing is evolving as a key computing platform for sharing resources like infrastructure, platform, software etc. This has proven to be an essential requirement for extending many existing applications. Software as a service (SaaS) is referred as on-demand software supplied by service providers in which software and associated data are ...
arxiv  

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