Results 111 to 120 of about 166,477,360 (253)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Software Quality Assurance as a Service: Encompassing the quality assessment of software and services

Future Generation Computer Systems
[EN] This paper introduces the Software Quality Assurance as a Service (SQAaaS) concept and it describes an open-source imple- mentation of a comprehensive platform that supports the automated assessment of specific quality metrics for software and services, defined as a set of baseline requirements.
Bernardo, Samuel, Orviz, Pablo, David, Mario, Gomes, Jorge, Arce, David, Naranjo, Diana, Blanquer, Ignacio, Campos, Isabel, Moltó, Germán, Pina, Joâo, EOSC-SYNERGY   +10 more
openaire   +4 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Quality of maternal and child health services in Tanzanian primary healthcare: a 2021–2022 star rating review

Reproductive Health
Background Tanzania faces high maternal and infant mortality rates, yet key service quality metrics remain underexamined, limiting targeted improvements. Star Rating Assessment (SRA), introduced in 2015, aims to improve primary health care (PHC) quality,
Erick S. Kinyenje, Martin M. Degeh, Joseph C. Hokororo, Syabo M. Mwaisengela, Ruth R. Ngowi, Omary A. Nassoro, Chrisogone J. German, Radenta P. Bahegwa, Yohanes S. Msigwa, Atuganile Musyani, Laura E. Marandu, Michael Habtu, Jennifer T. Mbise, Habibu Ismail, Janeth Masuma, Faraja Msemwa, Joanita Muruve, Saturini Manangwa, Daudi Msasi, Jimmy Mbelwa, Athman Pembe, Ahmad M. Makuwani, Ntuli A. Kapologwe, Tumaini J. Nagu, Eliudi S. Eliakimu   +24 more
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Annual report/ Connecticut Department of Revenue Services. FY 2007-2008.

, 2008
Annual; Description based on: 1982/1983.; Latest issue consulted: 2006/2007.; Fiscal years 2003/2004 and 2004/2005 combined.; Report year ends June 30.; Prepared by the Dept.
Connecticut. Dept. of Revenue Services.
core   +1 more source

EU-HTA Guidance for Clinical Validity: Misconceptions and Flawed Processes

Journal of Market Access & Health Policy
This review of the scope of the European Health Technology Assessment (EU HTA)’s guidance on clinical trial validity in its randomized controlled trials (RCTs) highlights several key issues that undermine its practical application and effectiveness ...
Mondher Toumi, Bruno Falissard, Asma Jouini, Samuel Aballéa, Laurent Boyer, Pascal Auquier   +5 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source