Results 201 to 210 of about 863,119 (264)

Regulation of the veterinary profession: the authorization to practice, origins, milestones, and emerging challenges. [PDF]

Front Vet Sci
Vaarten J, De Briyne N, van Herten J, De Vliegher S.   +3 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Human Islet. [PDF]

Cell Prolif
Zou J, Li S, Fu H, Zhang M, Hu A, Tian X, Du Y, Wei L, Chen X, Gao J, Liang R, Feng X, Li Y, Wang Y, Cai X, Sun P, Ding X, Zhang B, Liu T, Liu N, Hao J, Wang L, Zhao H, Cao J, Ma A, Zhu L, Li Q, Wei Q, Ding X, Cheng Y, Zhao T, Wang S.   +31 more
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

A theoretical approach to the remediation of saline streamflow conditions downstream of the Nwanedi catchment reservoir. [PDF]

Sci Rep
Gumbo AD, Kapangaziwiri E, Mugari E, Kativhu S, Manjoro M, Maswanganye SE, Machimana L, Nethengwe N.   +7 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Leveraging technologies for data management and sharing to foster collaboration and implement data spaces. [PDF]

Data Brief
Chrysakis I, Antzoulatos G, Sánchez L, Parreira JX, Skoutas D, Jayawardene I, Bernardo RD, Vargiu E, Vrochidis S, Mannens E.   +9 more
europepmc   +1 more source

Commentary on "Protecting Against Unintended Risk From Student Quality Improvement Projects in Health Care". [PDF]

Adv Health Inf Sci Pract
Watzlaf VJM.
europepmc   +1 more source

Development and Usability of a Dashboard for Quality Monitoring and Resident-Centered Care in Australian Residential Long-Term Care: Mixed-Methods Study. [PDF]

JMIR Hum Factors
Dendere R, Stockwell-Smith G, Lang M, Hargrave M, Mayfield S, Gray LC.   +5 more
europepmc   +1 more source